Visar resultat 1 - 5 av 691 avhandlingar innehållade ordet aging.
Sammanfattning : The overall purpose of this thesis is to describe, explore and illuminate inner strength among the oldest old. The thesis has a salutogenic perspective where strengths and health are in the foreground instead of weakness and ill health. The thesis is part of The Umeå 85+ study and comprises four studies with both quantitative and qualitative data. LÄS MER
Sammanfattning : This dissertation aims to contribute to the rectification of the atheoretization that characterizes the study of aging and diversity through the formulation and preliminary empirical testing of a culturally-relevant theoretical framework for the study of successful aging. Inspired by the Kluckhohnian approach to the study of cultural variation, the framework hereby proposed posits that there is congruence between the understandings of successful aging that people uphold and the value orientations that they prefer in regards to four topics: man-nature, time, activity and relational. LÄS MER
3. Aging Along the Hippocampal Axis : Structure, Function and Whole-brain Connections in Association with Memory
Sammanfattning : Hippocampus-dependent functions display marked reductions in older age, an observation that has led to the extensive study of age effects on hippocampal properties. Even though research indicates that the hippocampus is structurally and functionally heterogeneous along its longitudinal axis, its anterior and posterior regions differentially supporting episodic and spatial memory representations, few studies explicitly consider age effects in relation to axis. LÄS MER
Sammanfattning : As life expectancy increases, understanding challenges related to the processes of aging are more relevant than ever. Common age-related diseases progress as consequences of accumulative protein damage and protein aggregates. LÄS MER
Sammanfattning : Peroxiredoxins have emerged as conserved modulators of the rate of aging in yeast and multicellular organisms and play a role in lifespan extension through the anti-aging intervention caloric restriction. Yet, it is not clear through what mechanism peroxiredoxins extend lifespan. LÄS MER