Sökning: "Non-shivering thermogenesis"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden Non-shivering thermogenesis.

  1. 1. Comparative analysis of the thermogenic protein UCP1 across the mammalian phylogeny

    Författare :Michael James Gaudry; Martin Jastroch; Tobias Wang; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Uncoupling protein 1; Evolution; Non-shivering thermogenesis; Brown adipose tissue; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Uncoupling protein 1 (UCP1) drives mitochondrial inefficiency to produce heat in mammalian brown adipose tissue (BAT). Many mammalian species rely on this form of adaptive non-shivering thermogenesis (NST) to defend high body temperatures in the cold. LÄS MER

  3. 2. Amino acid-induced thermogenesis during anaesthesia

    Författare :Eva Brzezinska Selldén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : General anaesthesia causes hypothermia due to decreased metabolic rate and impaired thermoregulation. Adverse effects of hypothermia are coagulation disorders, wound infection, ischemic cardiac events and postoperative shivering. LÄS MER

  4. 3. Control of fatty acid utilization in brown adipose tissue

    Författare :Jan Nedergaard; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : In order to keep warm in cold surroundings, mammals have developed a mechanism for non-shivering thermogenesis. The major part of this heat production takes place in brown adipose tissue. The heat results from combustion of fatty acids. LÄS MER

  5. 4. Regulatory Factors that Reveal Three Distinct Adipocytes : The Brown, the White and the Brite

    Författare :Tomas B. Waldén; Jan Nedergaard; Stephen R. Farmer; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipocyte; UCP1; brite; brown; white; Hox Zic; miRNA; Physiology; Fysiologi; fysiologi; Physiology;

    Sammanfattning : Adipose tissues have long been considered to derive from a common origin. Even the functionally different brown and white adipose tissues were generalized to share a common origin. Brown adipose tissue is a highly innervated and vascularised tissue containing multilocular and multimitochondrial brown adipocytes. LÄS MER

  7. 5. The effects of glucocorticoids on brown fat : physiological and molecular studies

    Författare :Ineke Luijten; Jan Nedergaard; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Brown adipose tissue (BAT) is the main site for non-shivering thermogenesis in most mammals. The BAT-specific uncoupling protein-1 (UCP1) uncouples substrate oxidation from ATP production and hereby decreases metabolic efficiency. LÄS MER