Sökning: "opiate"

Visar resultat 1 - 5 av 24 avhandlingar innehållade ordet opiate.

  1. 1. Enterostatin - target proteins and intracellular mechanisms. Function in food intake and energy metabolism

    Författare :Karin Berger; Molekylär endokrinologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ATP; energy metabolism; insulin; uncoupling protein; beta-casomorphin; opiate; SK-N-MC; INS-1; Medicin människa och djur ; Medicine human and vertebrates ; fat intake; F1F0-ATP synthase; appetite; enterostatin; satiety; obesity;

    Sammanfattning : Hunger and satiety are the results of complex neural events that involve several neurotransmitters and peptides. Enterostatin is an appetite-regulating peptide released in the intestine in response to fat ingestion. Enterostatin specifically decreases fat intake, but has also metabolic effects like inhibition of insulin secretion. LÄS MER

  3. 2. Toxicological studies of opiate-related death

    Författare :Joakim Strandberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis comprises studies on opiate overdose death, and focuses on evaluation of toxicological characteristics including the possible influence of abstinence and polydrug use for the fatal outcome. In order to identify and classify drug abusers, a screening method for several drugs of abuse was developed and applied on randomly selected autopsy cases. LÄS MER

  4. 3. Mechanisms of opiate tolerance and dependence in the rat

    Författare :Orsolya Hoffman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Drug addiction is a complex phenomenon with various biological, psychological and social causes and consequences, which belongs to the major problems of today's society. Opiates have been used and misused for thousand of years and addiction to them develops both in humans and in animals. LÄS MER

  5. 4. In vitro and postmortem studies of the brain opioid system : association to opiate dependence

    Författare :Parisa Zarnegar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Opioid system; brain; gene expression; amygdala; hippocampus; opiate dependence;

    Sammanfattning : Opioids such as heroin are highly addictive illicit drugs. The μ opioid receptor (MOR) plays a central role in mediating the effects of opiates and related opioid. LÄS MER

  7. 5. En dyster parentes – opiatregeln i svensk LARO-behandling 2010–2016

    Författare :Bodil Monwell; Arne Gerdner; Björn Johnson; Per Bülow; Thomas Clausen; Jönköping University; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; opiates; opioids; opioid maintenance treatment; methadone; buprenorphine; regulation; National Board of Health and Welfare; opiater; opioider; opioidberoende; buprenorfin; metadon; läkemedelsassisterad behandling; föreskrift; Socialstyrelsen;

    Sammanfattning : Opioids are well documented to arouse euphoria, relieve pain, and to have a high dependency potential. Opioid dependence is a serious chronic condition with a high risk of extensive worsened health, relapse and premature death.Opioid maintenance treatment (OMT) is well researched and has strong scientific support. LÄS MER