Sökning: "Jan Nedergaard"
Visar resultat 1 - 5 av 15 avhandlingar innehållade orden Jan Nedergaard.
1. Control of fatty acid utilization in brown adipose tissue
Sammanfattning : In order to keep warm in cold surroundings, mammals have developed a mechanism for non-shivering thermogenesis. The major part of this heat production takes place in brown adipose tissue. The heat results from combustion of fatty acids. LÄS MER
2. Regulation and measurement of brown adipose tissue blood flow
Sammanfattning : Brown adipose tissue (BAT) is an organ specialized in macromolecule combustion in order to produce heat. Because of its high capacity to dissipate energy, it is currently among the best hopes for future treatments of obesity and diabetes. LÄS MER
3. Thermal physiology and metabolism : Interplay between heat generation and energy homeostasis
Sammanfattning : Mammal metabolism is intimately connected to the maintenance of body temperature. While metabolic pathways invariably produce heat as a by-product, the natural heat present in the environment also plays a role in defining the adaptive metabolism and general physiology of an organism. LÄS MER
4. Who is Who in the Adipose Organ : A look at the Heterogeneity of Adipocyte Biology
Sammanfattning : The increasing prevalence of obesity and related health complications, such as type 2 diabetes, cardiovascular disease and cancer, demands thorough investigation of the underlying processes. One of the key tissues investigated in this context is adipose tissue. LÄS MER
5. The secretome of brown adipose tissue
Sammanfattning : Brown adipose tissue has long been known for its heat-producing capacity, but less is known about its possible effects as a secretory organ. This thesis summarizes information about presently known factors secreted from brown adipose tissue and about their actions. We were able to add factors to the list by the use of a signal-sequence trap method. LÄS MER