Sökning: "trophoblast"
Visar resultat 16 - 20 av 21 avhandlingar innehållade ordet trophoblast.
16. Immune regulation at the fetal‐maternal interface with focus on decidual macrophages
Sammanfattning : A successful pregnancy requires that the maternal immune system adapts to tolerate the semi-allogeneic fetal-placental unit. This adaptation mainly occurs locally, i.e. at the fetal-maternal interface, where fetal-derived tissues come into close contact with maternal cells in the uterine endometrium (called decidua during pregnancy). LÄS MER
17. Immune cell composition and cytokine expression in the pregnant and non-pregnant uterus
Sammanfattning : The success of implantation and further development of the embryo is heavily dependent on the endometrial immune cell composition and its ability to communicate with fetal semi-allogeneic trophoblast cells. Although our understanding of the immune cell population in the uterus has improved, its precise role in normal reproduction and reproductive disorders is still not fully resolved. LÄS MER
18. Matrix metalloproteinase-26 (MMP-26) and Tissue inhibitor of metalloproteinases-4 (TIMP-4) in normal, hyperplastic, and malignant endometrium
Sammanfattning : The aim of the thesis was to study matrix metalloproteinase-26 (MMP-26) and tissue inhibitor of metalloproteinases-4 (TIMP-4) in normal, hyperplastic, and malignant endometrium. Most importantnly, both these molecules may be ivolved in the implantation process. Trophoblast tissue from human as well as mouse embryos produces pro-MMP-9. LÄS MER
19. Cytokines and immune balance in preeclampsia : a survey of some immunological variables and methods in the study of preeclampsia
Sammanfattning : Preeclampsia is one of the most feared pregnancy complications, with a risk of maternal and fetal death and with no ideal therapy readily available. The cause of this strictly pregnancyrelated disease is still unknown and is therefore a great challenge to all researchers in the field of pregnancy-related pathophysiology. LÄS MER
20. Immune cells in pregnant uterine mucosa : functional properties, cellular composition and tissue organization
Sammanfattning : The pregnant uterus mucosa - decidua - is an "immunologically privileged" site. A semiallogeneic embryo is allowed to survive, develop, and grow while the same tissue implanted outside the uterus will be rejected. The decidua basalis, which participates in the placenta formation, is a tissue rich in lymphoid cells. LÄS MER