Sökning: "stomach cancer"
Visar resultat 1 - 5 av 64 avhandlingar innehållade orden stomach cancer.
1. Tumors associated with Hereditary Nonpolyposis Colorectal Cancer: Defective Mismatch Repair and Familial Risk of Cancer
Sammanfattning : Inactivation of the DNA mismatch repair (MMR) system is a tumorigenic mechanism involved in 15-20% of tumor types such as colorectal and endometrial cancer and is specifically associated with the Hereditary Nonpolyposis Colorectal Cancer (HNPCC) syndrome. These MMR defective tumors are characterized by microsatellite instability (MSI), a phenomenon that reflects alterations in length of repeated sequences, and 90% of MSI tumors show loss of immunohistochemical expression for the MMR protein affected. LÄS MER
2. Genomic Profiling, Mutations and Deranged Signaling in Esophageal Cancer and Hereditary Colorectal Cancer
Sammanfattning : Esophageal cancer and colorectal cancer represents two major types of gastrointestinal tumors. Though refined surgery and introduction of novel chemotherapeutics have improved outcome, more than 2500 Swedes die from these diseases every year. Novel markers for early diagnosis, prognosis and treatment prediction are therefore needed. LÄS MER
3. Asthma and cancer among pulp and paper mill workers
Sammanfattning : There were two main aims of this thesis. One was to study if repeated high exposures to irritant gases give rise to new-onset asthma, and the other was to study if exposure in pulp and paper mills were associated with cancer. LÄS MER
4. The LRIG-family: identification of novel regulators of ErbB signaling with clinical implications in astrocytoma
Sammanfattning : Astrocytic tumors are the most common malignancies of the central nervous system, accounting for more than 60% of all primary brain tumors. The prognosis for high grade astrocytoma patients is dismal and there is no curative treatment, today. LÄS MER
5. Enteric Helicobacter and H. pylori in chronic inflammation and cancer of the hepatobiliary tract and pancreas
Sammanfattning : The Helicobacter genus now consists of at least 26 species, with additional novel species in the process of being validated. Beyond the impact of H. LÄS MER