Sökning: "copy number analysis"
Visar resultat 1 - 5 av 125 avhandlingar innehållade orden copy number analysis.
- Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis
Sammanfattning : By accurately describing cancer genomes, we may link genomic mutations to phenotypic effects and eventually treat cancer patients based on the molecular cause of their disease, rather than generalizing treatment based on cell morphology or tissue of origin.Alteration of DNA copy number is a driving mutational process in the formation and progression of cancer. LÄS MER
- Detta är en avhandling från Stockholm : Department of Biochemistry and Biophysics, Stockholm University
Sammanfattning : Every tumour is unique and characterised by its genetic, epigenetic, phenotypic, and morphological signature. The diversity observed between and within tumours, and over time, is termed tumour heterogeneity. An increased heterogeneity within a tumour correlates with cancer progression, higher resistance rates, and poorer outcome. LÄS MER
- Detta är en avhandling från Göteborg : University of Gothenburg
Sammanfattning : With the continued accumulation of genomic data at ever increasing resolution the challenge ahead lies in reading out meaningful clinical/biological information form the data that can contribute to a better understanding of the cancerous process. The need for novel approaches, new statistical methods is therefore strong. LÄS MER
4. Interpreting the Script Image Analysis and Machine Learning for Quantitative Studies of Pre-modern ManuscriptsDetta är en avhandling från Göteborg : University of Gothenburg
Sammanfattning : The humanities have for a long time been a collection of fields that have not gained from the advancements in computational power, as predicted by Moore´s law. Fields like medicine, biology, physics, chemistry, geology and economics have all developed quantitative tools that take advantage of the exponential increase of processing power over time. LÄS MER
- Detta är en avhandling från Department of Oncology, Clinical Sciences, Lund University
Sammanfattning : Cancer is a genetic disease that arises when a cell acquires unlimited growth potential through a series of mutational events, which target genes essential for normal cell control and maintenance. Breast cancer is one of the most frequent malignancies in women worldwide, and it is characterized by heterogeneous tumor biology, histological subtypes, variable prognosis and variable responsiveness to treatment. LÄS MER