Sökning: "Familial Risk of Cancer"
Visar resultat 1 - 5 av 68 avhandlingar innehållade orden Familial Risk of Cancer.
- Detta är en avhandling från Umeå : Umeå universitet
Sammanfattning : In spite of the fact that prostate cancer is the most common male cancer in both Sweden and many other countries in the developed world, little is known of risk factors and predisposing conditions. The only well recognized risk factors are age, race and familial aggregation. LÄS MER
2. Tumors associated with Hereditary Nonpolyposis Colorectal Cancer: Defective Mismatch Repair and Familial Risk of CancerDetta är en avhandling från Department of Oncology, Clinical Sciences, Lund University
Sammanfattning : Inactivation of the DNA mismatch repair (MMR) system is a tumorigenic mechanism involved in 15-20% of tumor types such as colorectal and endometrial cancer and is specifically associated with the Hereditary Nonpolyposis Colorectal Cancer (HNPCC) syndrome. These MMR defective tumors are characterized by microsatellite instability (MSI), a phenomenon that reflects alterations in length of repeated sequences, and 90% of MSI tumors show loss of immunohistochemical expression for the MMR protein affected. LÄS MER
3. Genetic factors in childhood cancer. Associations between tumors in childhood and adulthood, and prevalence of germline TP53 mutationsDetta är en avhandling från Department of Oncology, Clinical Sciences, Lund University
Sammanfattning : The etiology of childhood cancer is largely unknown. Approximately 1-10% of all childhood tumors are associated with known cancer predisposition syndromes. However, the contribution may be underestimated due to the failure to detect patients with genetic susceptibility for cancer when relying on known family pattern and anomalies. LÄS MER
- Detta är en avhandling från Division of Urological Cancers
Sammanfattning : Prostate cancer is the second most common cancer in men. In order to improve diagnosis and prognosis, new sensitive and specific biomarkers are needed. Tissue biomarkers carry expression and morphological information of the tissue where they are expressed. LÄS MER
5. Insights into breast cancer: New familial patterns and identification of a potential predictive markerDetta är en avhandling från Division of Oncology and Pathology
Sammanfattning : The last proportion of heredity in breast cancer has proven to be somewhat elusive despite massive attempts to identify the associated factors. Approximately 50 percent of breast cancer caused by familial factors is currently explained. LÄS MER