Sökning: "recruitment generation"

Visar resultat 11 - 15 av 46 avhandlingar innehållade orden recruitment generation.

  1. 11. Dendritic cell and IgA responses in SIV and HIV-1 pathogenesis

    Författare :Johan Söderlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DC; SIV; HIV-1; macaques; neutralizing antibodies; IgA;

    Sammanfattning : Simian immunodeficiency virus (SIV) as well as human immunodeficiency virus (HIV-1) can infect different subsets of dendritic cells (DC). Such cells may therefore not only be involved in the generation of recruitment of naïve T and B lymphocytes in induction of SIV/HIV-1 specific adaptive responses but also transmit virus from port of entrance to the secondary lymphoid compartment generating systemic viral spread. LÄS MER

  3. 12. Endothelial : mural cell interplay in regulation of blood- and lymph vessel development and function

    Författare :Yixin Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Blood- and lymphatic vascular development and homeostasis depend on correct endothelial- mural cell interaction, and dysregulation thereof is apparent in multiple human diseases. However the mechanisms controlling the formation of these respective vascular systems are not fully understood. LÄS MER

  4. 13. Regulation of gene expression in fruit flies : how does it start, and will it be remembered?

    Författare :Aman Zare; Per Stenberg; Yuri B. Schwartz; Åsa Rasmuson-Lestander; Guillaume Filion; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Drosophila; epigenetics; transcription; gene regulation; transcription maintenance; CBP; polymerase pausing; Polycomb group proteins; transgenerational inheritance of transcriptional response; gut microbiome; molekylärbiologi; Molecular Biology;

    Sammanfattning : One of the most distinctive features of eukaryotic chromosomes is the bundling of DNA together with functionally associated RNA and proteins in chromatin. This allows huge amounts of DNA to be packed inside the very tiny space of the nucleus, and alterations in the structure of chromatin enable access to the DNA for transcription (“reading” genes by production of RNA copies). LÄS MER

  5. 14. Essays on Discrimination in Hiring

    Författare :Magnus Carlsson; Dan-Olof Rooth; Jan Ekberg; Petter Lundborg; Växjö universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; ethnic discrimination; sex discrimination; sex segregation; correspondence testing; situation testing; field experiments; hiring; job search; exit from unemployment; Economics; Nationalekonomi; Economics; Nationalekonomi;

    Sammanfattning : This thesis consists of four self-contained essays on discrimination in hiring. Essay I (co-authored with Dan-Olof Rooth) present evidence of ethnic discrimination in the recruitment process by sending fictitious applications to real job openings. LÄS MER

  7. 15. On CXC Chemokines in Endotoxin-Induced Liver Injury

    Författare :Xiang Li; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ortopedi; traumatologi; orthopaedics; traumatology; Kirurgi; Surgery; patologisk anatomi; Patologi allmän ; pathological anatomy; General pathology; intravital microscopy; liver damage; Adhesion; CXC chemokines;

    Sammanfattning : Leukocyte recruitment is a rate-limiting step in endotoxemic liver injury. Leukocyte extravasation is a multistep process, supported by multiple combinations of adhesion molecules and chemokine receptors. This thesis examined the mechanisms of activation, adhesion and extravascular infiltration of leukocytes in endotoxin-induced liver injury. LÄS MER