Sökning: "gene regulation"

Visar resultat 1 - 5 av 1683 avhandlingar innehållade orden gene regulation.

  1. 1. Tripeptidyl-Peptidase II : Structure, Function and Gene Regulation

    Författare :Ann-Christin Lindås; Birgitta Tomkinson; Mikael Widersten; Ralf Morgenstern; Uppsala universitet; []
    Nyckelord :Biochemistry; gene regulation; protein expression; enzyme kinetics; tripeptidyl-peptidase II; proteasome; intracellular protein degradation; exopeptidase; Biokemi;

    Sammanfattning : The protein degradation process is of vital importance for the cell to maintain cellular functions. An important enzyme in this process is the multimeric tripeptidyl-peptidase II (TPP II). It removes tripeptides from a free N-terminus of the substrates. LÄS MER

  2. 2. Contributions to Statistical Analysis of Gene Expression Data

    Författare :Anders Sjögren; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA microarray; differential expression; gene regulation; variance stabilising transformation; permutation; reference gene; housekeeping gene; bootstrap; quality control QC ; quality assurance QA ; quality assessment; empirical Bayes; weighted moderated t-statistic; WAME; DNA microarray;

    Sammanfattning : .... LÄS MER

  3. 3. Treatment of Skin Wounds with Cell Transplantation and Gene Transfer

    Författare :Tor Svensjö; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pigs; gene regulation; cell culture; fibroblasts; keratinocytes; wound healing; skin; gene transfer; Transplantation; gene therapy; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : Background: A large number of different wound coverings have been used in order to improve the wound microenvironment, and thus accelerate repair. Since almost two centuries, clinicians and researchers have developed techniques for skin transplantation. LÄS MER

  4. 4. Computational Modelling of Gene Regulation in Cancer : Coding the noncoding genome

    Författare :Husen Muhammad Umer; Jan Komorowski; Claes Wadelius; Jan Korbel; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Regulatory elements; gene regulation; cancer; motif; integrative database; software solutions for cancer data; Bioinformatics; Bioinformatik;

    Sammanfattning : Technological advancements have enabled quantification of processes within and around us. The information stored within our body converts into petabytes of data. Processing and learning from such data requires comprehensive computational programs and software systems. LÄS MER

  5. 5. Regulation of gene expression in fruit flies : how does it start, and will it be remembered?

    Författare :Aman Zare; Per Stenberg; Yuri B. Schwartz; Åsa Rasmuson-Lestander; Guillaume Filion; Umeå universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Drosophila; epigenetics; transcription; gene regulation; transcription maintenance; CBP; polymerase pausing; Polycomb group proteins; transgenerational inheritance of transcriptional response; gut microbiome; molekylärbiologi; Molecular Biology;

    Sammanfattning : One of the most distinctive features of eukaryotic chromosomes is the bundling of DNA together with functionally associated RNA and proteins in chromatin. This allows huge amounts of DNA to be packed inside the very tiny space of the nucleus, and alterations in the structure of chromatin enable access to the DNA for transcription (“reading” genes by production of RNA copies). LÄS MER