Sökning: "electrophysiology"

Visar resultat 11 - 15 av 94 avhandlingar innehållade ordet electrophysiology.

1. 11. Allopregnanolone effects on food intake and weight gain

   Författare :Ellinor Holmberg; Torbjörn Bäckström; Bo Söderpalm; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allopregnanolone; neurosteroid; GABA; GABAA receptor; food intake; weight gain; obesity; hyperphagia; diurnal rhythm; schedule feeding; high fat diet; electrophysiology; obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : Background Obesity is currently one of the major causes of ill health and it is clear that overeatingis the cause of obesity. However, the actions of many endogenous factors that contribute to overeating are still not well understood. LÄS MER

3. 12. CRISPR/Cas9-based therapies and the role of astrocytes in Alzheimer’s disease and Parkinson’s disease

   Författare :Evangelos Konstantinidis; Martin Ingelsson; Anna Erlandsson; Vilmantas Giedraitis; Magnus Essand; Harald Steiner; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer s disease; Parkinson s disease; gene editing; CRISPR Cas9; amyloid-beta; astrocytes; neurons; iPSCs; electrophysiology;

   Sammanfattning : Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two most common neurodegenerative disorders. Whereas the AD brain features plaques of amyloid-beta (Aβ) and neurofibrillary tangles of tau, the PD brain is characterized by Lewy bodies and Lewy neurites containing α-synuclein (αSyn). LÄS MER

4. 13. Neural Interfaces to the Odour World of Scarab Beetles

   Författare :Mattias Larsson; Biologiska institutionen; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Djurekologi; Animal ecology; Intra; Antennal lobe; CNS; Attraction; Olfactometer; Behaviour; Mass spectrometry; Gas chromatography; Electrophysiology; Single sensillum; Receptor neuron; Plant volatile; Sex pheromone; Neuroethology; Odour detection; Olfaction; Coleoptera; Scarabaeidae; Entomology; plant parasitology; Entomologi; växtparasitologi; Environmental chemistry; Miljökemi;

   Sammanfattning : Antennal detection and central nervous integration of behaviourally relevant odours in scarab beetles (Coleoptera: Scarabaeidae) was investigated, using the two Japanese scarabs Anomala cuprea and Phyllopertha diversa (Rutelinae), and the Central African fruit chafer Pachnoda marginata (Cetoniinae) as model species. Electrophysiological single cell recordings in A. LÄS MER

5. 14. Endogenous modulators of hyperexcitability in epilepsy: electrophysiological and optogenetic delineation of neuropeptide Y mechanisms in interneurons

   Författare :Marco Ledri; Lund Neurologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; interneurons; Epilepsy; Neuropeptide Y; synaptic transmission; synaptic plasticity; electrophysiology; optogenetics;

   Sammanfattning : Epilepsy is one of the most common neurological disorders worldwide, affecting 1% of the general population, and is characterized by a predisposition for the generation of epileptic seizures. Despite having several different aetiologies, a common underlying cause of epilepsy seems to be an acquired imbalance between excitatory and inhibitory circuits in the brain, which leads to hyperexcitability and appearance of seizures. LÄS MER

7. 15. Acute coronary syndromes. The prognostic importance of hypertension, diabetes and vectorcardiographic markers

   Författare :Markus Lingman; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute coronary syndromes; hypertension; diabetes; percutaneous coronary intervention; prognosis; myocardial ischemia; coronary artery disease; electrocardiography; vectorcardiography; arrhythmia; sudden death; electrophysiology;

   Sammanfattning : Research questions: 1 Is hypertension and diabetes associated with the future risk of death, and recurrent manifestations of cardiovascular disease in acute coronary syndromes (ACS)? 2 How does myocardial ischemia affect depolarization and repolarization of the heart during the early phase of an acute myocardial infarction? 3 What is the prognostic value of accepted vectorcardiographic markers in relation to future risk of sudden cardiac death after ACS? Methodology: Papers I, III and IV studied patients with ACS prospectively and consecutively included at the coronary care unit of Sahlgrenska University Hospital. Paper I deals with 2,329 patients who were followed for a median of 8 years. LÄS MER