Sökning: "Lund Neurologi"
Visar resultat 1 - 5 av 124 avhandlingar innehållade orden Lund Neurologi.
1. Stroke epidemiology in Southern Sweden. Trends in incidence and survival across two decades with projections into the future
Sammanfattning : Background: Stroke is a major cause of death and disability. Investigations of the epidemiological trends for stroke might result in better understanding of stroke pathogenesis and prevention. LÄS MER
2. Experimental Stroke and Neurotrophins: Regulation, function and gene transfer of neurotrophins in rat and mouse models of focal cerebral ischemia
Sammanfattning : Stroke caused by focal cerebral ischemia is a major cause of death and neurological disability in humans. The forebrain region most commonly affected by ischemic incidents is that supplied by the middle cerebral artery. LÄS MER
Sammanfattning : In this thesis, two potential endogenous mechanisms for neuronal survival and repair have been investigated in a rat model of stroke, middle cerebral artery occlusion (MCAO): signaling of the GDNF family of neurotrophic factors, and neurogenesis from endogenous progenitor cells. As determined by in situ hybridization for GDNF family ligand and receptor genes, MCAO caused widespread upregulation of both components of the functional GDNF receptor, c-Ret and GFRalpha1, indicating that GDNF may be a survival signal in stroke. LÄS MER
Sammanfattning : Multiple sclerosis (MS) is a chronic disease of the central nervous system, characterized by focal inflammatory lesions with demyelination and axonal loss. It is believed that MS is an immune-mediated disorder with both genetic and environmental contributions to the pathogenesis. LÄS MER
Sammanfattning : Stroke in young adult rodents triggers neurogenesis in the damaged striatum and intact hippocampus. as stroke happens frequently in aged individuals it is of great importance to know whether aging affects brain recovery mechanisms. LÄS MER