Avancerad sökning

Visar resultat 1 - 5 av 84 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Regeneration in the adult brain after focal cerebral ischemia : exploration of neurogenesis and angiogenesis

   Författare :Wei Jiang; Jukka Jolkkonen; Umeå universitet; []
   Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; neurogenesis; angiogenesis; rats; mice; gliosis; BrdU; CBF; protein synthesis; ATP; penumbra; reperfusion; VEGF; 3-D confocal; photothrombosis; MCAO; Medicine; Medicin;

   Sammanfattning : Background: Ischemic stroke ranks as the third major cause of clinical mortality and the leading cause of handicap in adults. Each year, stroke occurs in about 30,000 Swedes. The severity of an acute ischemic stroke depends mainly on the degree and duration of local cerebral blood flow (lCBF) reduction. LÄS MER

3. 2. Adult Neural Stem Cells-Influence of Stroke, Inflammation and Aging

   Författare :Henrik Ahlenius; Lund Neurologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammation; Neural stem cells; adult; neurogenesis; stroke; aging; TNF-R1; TNF-α;

   Sammanfattning : Neural stem cells (NSCs) in the embryo generate neurons, astrocytes and oligodendrocytes, the principal cells of the central nervous system (CNS), which contribute to the full diversity of the brain. Some NSCs persist in the adult brain and ensures neurogenesis throughout adult life in the subventricular zone (SVZ) and the subgranular zone (SGZ). LÄS MER

4. 3. Brain Inflammation and Adult Hippocampal Neurogenesis in Epilepsy

   Författare :Deepti Chugh; Lund Neurologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epilepsy; Inflammation; Neurogenesis; Hippocampus; Microglia; Adhesion molecules; Scaffolding proteins;

   Sammanfattning : Epilepsy is a severe chronic neurological disorder characterized by recurrent spontaneous seizures. Excitatory/inhibitory (E/I) imbalance, neuronal loss, brain inflammation, and altered adult neurogenesis are some of the characteristic hallmarks of epilepsy. LÄS MER

5. 4. Neurogenesis in the adult brain from ballyhoo to sobriety

   Författare :Helena Frielingsdorf; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; neurofysiologi; Neurologi; neurophysiology; neuropsychology; Neurology; Nerve growth factor; acetylcholine; GABA; learning; hippocampus; Neurogenesis; dopamine; substantia nigra;

   Sammanfattning : New neurons are spontaneously generated in two regions of the adult brain, the hippocampus and the subventricular zone/olfactory bulb. The objective of this thesis was to study potential implications for adult neurogenesis in Alzheimer's (AD) and Parkinson's diseases (PD). LÄS MER

7. 5. Long-term neurogenesis after stroke in the adult rat brain

   Författare :Pär Thored; Lund Neurologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; embryologi människa ; Neurology; neuropsychology; neurophysiology; Utvecklingsbiologi; teratologi; embryology human ; ontogeny; Development biology; teratology; Stroke; Stem Cells; Neurogenesis; neurofysiologi; Clinical biology; Klinisk biologi; Neurologi; neuropsykologi;

   Sammanfattning : Stroke is a leading cause of death and disability for which there is no treatment for functional recovery. Following stroke, striatal neurogenesis is increased, with newly formed neuroblasts migrating towards the damage. This response has so far been considered acute and transient. LÄS MER