Sökning: "protein synthesis"

Visar resultat 1 - 5 av 844 avhandlingar innehållade orden protein synthesis.

  1. 1. Tailoring of Biomaterials using Ionic Interactions : Synthesis, Characterization and Application

    Författare :Björn Atthoff; Jöns Hilborn; Tim Bowden; Mats Andersson; Uppsala universitet; []
    Nyckelord :Chemistry; biodegradable polymers; ionomer; water uptake; protein delivery; protein adsorption; protein membrane; cell seeding efficiency; amphiphillic; inner structure; polarized membrane; Kemi;

    Sammanfattning : The interactions between polymers and components of biological systems are an important area of interest within the fields of tissue engineering, polymer chemistry, medicine and biomaterials. In order to create such a biomimetic material, it must show the inherent ability to reproduce or elicit a biological function. LÄS MER

  3. 2. Macrolide Antibiotics in Bacterial Protein Synthesis

    Författare :Martin Lovmar; Måns Ehrenberg; Tanel Tenson; Peter B. Moore; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; protein synthesis; macrolides; resistance; initiation of translation; non-competitive inhibitors; kinetics; translation accuracy; proof-reading; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : Macrolides are a large group of clinically relevant antibiotics that inhibit protein synthesis by binding to the large ribosomal subunit in the peptide exit tunnel, close to the peptidyl transferase center (PTC). We have shown that the peptide length of the resulting peptidyl-tRNA drop-off products is proportional to the distance between the PTC and the respective macrolide in the tunnel. LÄS MER

  4. 3. Protein modularity : Structure and interactions by NMR and SPR

    Författare :Amélie Wallenhammar; Maria Sunnerhagen; Björn Wallner; Lotta Tollstoy-Tegler; Helena Berglund; Linköpings universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : Protein degradation is a fundamental cornerstone of regulation of protein levels in the human body. For proper function, numerous molecular processes rely on fine-tuned communication through specific interactions between proteins. LÄS MER

  5. 4. Proofreading during protein synthesis

    Författare :Tarmo Ruusala; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  7. 5. Rate and Accuracy of Bacterial Protein Synthesis

    Författare :Magnus Johansson; Måns Ehrenberg; Jon Lorsch; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; protein synthesis; ribosome; peptidyl transfer; rate-accuracy trade-off; kinetics; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : High levels of accuracy in transcription, aminoacylation of tRNA, and mRNA translation are essential for all life forms. However, high accuracy also necessarily means large energy dissipation and slow kinetics. Therefore, in vivo there is a fine tuned balance between rate and accuracy of key chemical reactions. LÄS MER