Sökning: "VEGF"

Visar resultat 1 - 5 av 237 avhandlingar innehållade ordet VEGF.

  1. 1. Hypoxia, PDGF and VEGF in Vascular Development

    Författare :Ingrid Nilsson; Lena Claesson-Welsh; Randall Johnson; Uppsala universitet; []
    Nyckelord :Cell biology; hypoxia; VEGF; VEGFR-3; PDGF; endothelial cell; embryonic stem cell; angiogenesis; lymphangiogenesis; Cellbiologi;

    Sammanfattning : The mechanisms behind many important aspects of blood- and lymphatic vessel formation have yet not been elucidated in detail. The primary objectives of this thesis have therefore been to study the effects of hypoxia, platelet-derived growth factor (PDGF) and vascular endothelial growth factors (VEGFs) on vascular development and function. LÄS MER

  2. 2. Vascular Endothelial Growth Factor (VEGF) and Peripheral Nerve Regeneration

    Författare :Mariann Sondell; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Schwann cell; SCG; rat; peripheral nerve regeneration; neuropilin-1; nerve repair; mouse; growth factor; flk-1; axonal outgrowth; DRG; VEGF; Animal physiology; Djurfysiologi;

    Sammanfattning : This thesis concerns vascular endothelial growth factor (VEGF) and its possible role as a neurotrophic factor. I have investigated the effect of VEGF on neurons in culture but also in vivo, following a crush lesion of the sciatic nerve, and following nerve repair. LÄS MER

  3. 3. Macrophage expression of VEGF and VEGFR-1. Potential involvement in atherogenesis

    Författare :Linda Salomonsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :atherosclerosis; macrophages; oxLDL; statins; VEGF; VEGFR-1;

    Sammanfattning : The vascular endothelial growth factor (VEGF) family is a group of proteins which contributes to both neovascularisation and inflammation. Elevated levels of VEGF have been found in subjects with atherosclerosis and correlate to several cardiovascular risk factors, e.g. hypertension and hyperlipidemia. LÄS MER

  4. 4. The Role of Shb in Angiogenesis, FGF and VEGF Signalling in Endothelial Cells

    Författare :Kristina Holmqvist; Michael Welsh; Eva Degerman; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Shb; Src; FAK; Angiogenesis; VEGFR-2; FGFR-1; Endothelial cells; Spreading; Stress fiber formation; siRNA; VEGF; FGF; Differentiation; Migration; Tube formation; RNAi; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Angiogenesis is defined as the formation of new capillary blood vessels from pre-existing ones. This process involves several steps including: migration, proliferation and differentiation of endothelial cells into blood vessels. LÄS MER

  5. 5. Vascular endothelial growth factor in renal cell carcinoma

    Författare :Jan Jacobsen; Börje Ljungberg; Kjell Grankvist; Torgny Rasmuson; Anders Bergh; Peter Ekman; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; VEGF; isoforms; quantitative RT-PCR; immunohistochemistry; tissue microarray; Western blot; stage; survival; renal cell carcinoma; Urology and andrology; Urologi och andrologi;

    Sammanfattning : Background. Angiogenesis is essential for tumour growth. Vascular endothelial growth factor (VEGF) and its isoforms were investigated in relation to the clinical course in a large number of patients with renal cell carcinoma (RCC). Methods. LÄS MER