Sökning: "Reporter"

Visar resultat 11 - 15 av 335 avhandlingar innehållade ordet Reporter.

  1. 11. STAT5 expression and regulation in mammary epithelial cells

    Författare :Hanne Olsen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :STAT5; JAK2; PPAR-gamma; ER; MAPK; mammary epithelial cell differentiation;

    Sammanfattning : The mammary gland of an adult mammal undergoes cycles of proliferation and differentiation influenced by growth factors, peptide, and steroid hormones, e.g. epidermal growth factor (EGF), prolactin (PRL) and estrogen (E). LÄS MER

  3. 12. Bacteria-based methods for engineering and characterization of proteases and affinity proteins

    Författare :Lisa Sandersjöö; John Löfblom; Stefan Ståhl; Brent Iverson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioteknologi; Biotechnology;

    Sammanfattning : This thesis is focused on the development of methods for characterization and engineering of both proteases and affinity proteins. In addition, a prodrug concept for small affinity proteins is developed.Two of the developed methods are for engineering and/or characterization of proteases. LÄS MER

  4. 13. Reportaget som berättelse : En narratologisk undersökning av reportagegenren

    Författare :Cecilia Aare; Helena Bodin; Erik van Ooijen; Per Krogh Hansen; Stockholms universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Structural Narratology; Reportage; Literary Journalism; Directed Reality; Contextual Commitment; Textual Commitment; Narrative Empathy; Narrative Compassion; Literature; litteraturvetenskap;

    Sammanfattning : This study ­is the first dissertation where the genre of reportage (in the U.S. classified as literary journalism) is systematically mapped with the help of narratology. Using tools primarily from structural discourse narratology, the thesis examines, describes and maps written reportages as narratives. LÄS MER

  5. 14. In vivo properties of neural stem cells after transplantation into the rat brain-Studies of phenotypic differentiation and functional integration using cell-specific labelling and electrophysiological techniques

    Författare :Ulrica Englund Johansson; Peter Eriksson; Lund Oftalmologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell line; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; functional integration; electrophysiology; retrograde tracing; immortalized; GFP; migration; axonal projections; glia; neuron; transplantation; stem cell. progenitor cell; CNS; Biomedical Sciences;

    Sammanfattning : In the present thesis, we have examined the in vivo properties of in vitro expanded human and rat neural stem-and progenitor cells after transplantation into the neonatal and adult rat brain. The survival and differentiation of the grafted cells were assessed using species-specific antisera, and pre-labelling with the reporter gene green fluorescent protein (GFP). LÄS MER

  7. 15. The ADAR editing enzymes as therapeutic targets

    Författare :Kajsa Fritzell; Marie Öhman; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Editing by deamination of adenosine to inosine (A-to-I) in double-stranded RNA is a common event in the human transcriptome. Altered levels of the essential ADAR1 activity are associated with disease. Children with mutations in the ADAR1 gene suffer from fatal Aicardi-Goutières syndrome (AGS) characterized by aberrant interferon expression. LÄS MER