Sökning: "Kajsa Fritzell"

Hittade 1 avhandling innehållade orden Kajsa Fritzell.

1. 1. The ADAR editing enzymes as therapeutic targets

   Författare :Kajsa Fritzell; Marie Öhman; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; molekylär biovetenskap; Molecular Bioscience;

   Sammanfattning : Editing by deamination of adenosine to inosine (A-to-I) in double-stranded RNA is a common event in the human transcriptome. Altered levels of the essential ADAR1 activity are associated with disease. Children with mutations in the ADAR1 gene suffer from fatal Aicardi-Goutières syndrome (AGS) characterized by aberrant interferon expression. LÄS MER