Sökning: "mammary epithelial cell differentiation"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden mammary epithelial cell differentiation.

  1. 1. Transcriptional and Epigenetic Regulation of Epithelial-Mesenchymal Transition

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :E-Jean Tan; Uppsala universitet.; Uppsala universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TGFβ; EMT; HMGA2; Snail; Twist; E-cadherin; epigenetics; invasion; Molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : The transforming growth factor beta (TGFβ) is a cytokine that regulates a plethora of cellular processes such as cell proliferation, differentiation, migration and apoptosis. TGFβ signals via serine/threonine kinase receptors and activates the Smads to regulate gene expression. LÄS MER

  2. 2. Estrogen receptor signalling in mammary epithelial cells

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Medical Nutrition

    Författare :Malin Hedengran Faulds; Karolinska Institutet.; Karolinska Institutet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ER; STAT5; mammary epithelial cell differentiation; EGF; DAX-1;

    Sammanfattning : The mammary gland is a complex tissue going through cycles of extensive proliferation and differentiation. Many hormones are involved in the regulation of development of the mammary gland, including estrogen, prolactin and epidermal growth factor (EGF). LÄS MER

  3. 3. STAT5 expression and regulation in mammary epithelial cells

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Medical Nutrition

    Författare :Hanne Olsen; Karolinska Institutet.; Karolinska Institutet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; STAT5; JAK2; PPAR-gamma; ER; MAPK; mammary epithelial cell differentiation;

    Sammanfattning : The mammary gland of an adult mammal undergoes cycles of proliferation and differentiation influenced by growth factors, peptide, and steroid hormones, e.g. epidermal growth factor (EGF), prolactin (PRL) and estrogen (E). LÄS MER

  4. 4. Hypoxia and Hypoxia-Inducible Factors in Normal and Malignant Breast Epithelium

    Detta är en avhandling från Department of Laboratory Medicine, Lund University

    Författare :Karolina Helczynska; Lund University.; Lunds universitet.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Differentiation; Hypoxia; Breast cancer; Breast; HiF-1; HiF-2; 3D-cultures; prognosis;

    Sammanfattning : Breast cancer treatment is based on tumor and patient related factors such as tumor stage, grade, hormonal status, HER2 status, patient age, and family history to name a few. It is today widely acknowledged that hypoxia and hypoxia-inducible factors (HIF:s) contribute to tumor progression. LÄS MER

  5. 5. Transport proteins in mammary epithelial cells : studies in murine (HC11) and bovine (BME-UV) cells - effects of prochloraz

    Detta är en avhandling från ; Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences

    Författare :Yagmur Yagdiran; Sveriges lantbruksuniversitet.; [2015]
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Transporters localized in membranes of secreting mammary epithelial cells are involved in delivery of essential nutrients into milk. However, drugs and other xenobiotics may be substrates of these transporters and thus be actively secreted into milk, which may pose a health threat to breastfed infants and dairy consumers. LÄS MER