Sökning: "NATURVETENSKAP Biologi Cell- och molekylärbiologi Immunologi"

Visar resultat 1 - 5 av 53 avhandlingar innehållade orden NATURVETENSKAP Biologi Cell- och molekylärbiologi Immunologi.

  1. 1. Genetic and Epigenetic Profiling of Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Anna Margrét Halldórsdóttir; Uppsala universitet.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mantle cell lymphoma; chronic lymphocytic leukemia; copy number aberration; proliferation signature; TP53; SNP array; methylation array; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Haematology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Hematologi; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik; NATURAL SCIENCES Biology Cell and molecular biology Molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Molekylärbiologi; MEDICINE Morphology; cell biology; pathology Morphology Tumour biology; MEDICIN Morfologi; cellbiologi; patologi Morfologi Tumörbiologi; Medical Genetics; Medicinsk genetik; Oncology; Onkologi; Molekylär medicin; Molecular Medicine; Pathology; Patologi;

    Sammanfattning : Mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL) both belong to the group of mature B-cell malignancies. However, MCL is typically clinically aggressive while the clinical course of CLL varies. LÄS MER

  2. 2. Adenovirus for Cancer Therapy With a Focus on its Surface Modification

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Di Yu; Uppsala universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; cancer; therapy; neuroblastoma; neuroendocrine; modification; Tat; PTD; cell penetrating peptide; Helicobacter pylori; NAP; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Klinisk virologi; Clinical Virology; Medical Virology; Medicinsk virologi; Molekylär medicin; Molecular Medicine; Molekylär bioteknik; Molecular Biotechnology;

    Sammanfattning : Adenovirus serotype 5 (Ad5) is widely used as an oncolytic agent for cancer therapy. However, its infectivity is highly dependent on the expression level of coxsackievirus-adenovirus receptor (CAR) on the surface of tumor cells. LÄS MER

  3. 3. Vascular targeting for enhanced cancer immunotherapy

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Maria Georganaki; Uppsala universitet.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer immunotherapy; tumor vasculature; endothelial activation; IDO1; ELTD1; tertiary lymphoid organ; Biologi; Biology;

    Sammanfattning : Induced angiogenesis and chronic inflammation are major components of tumor immunosuppression. The scope of this thesis is to understand the role of the vasculature in anti-tumor immunity and thereby to improve cancer immunotherapy. LÄS MER

  4. 4. Molecular and Cellular Complexity of Glioma Highlights on the Double-Edged-Sword of Infiltration Versus Proliferation and the Involvement of T Cells

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Demet Çağlayan; Uppsala universitet.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioma; Sox2; Sox21; Snail; Bone morphogenetic protein; Sleeping Beauty; Gliomatosis Cerebri; T lymphocytes; T regulatory lymphocytes; Oncology; Onkologi; Biology; Biologi;

    Sammanfattning : Glioblastoma multiforme (GBM), the most common and malignant brain tumor, is characterized by high molecular and cellular heterogeneity within and among tumors. Parameters such as invasive growth, infiltration of immune cells and endothelial proliferation contribute in a systemic manner to maintain the malignancy. LÄS MER

  5. 5. Two Types of Fibrils in ATTR Amyloidosis Implications for Clinical Phenotype and Treatment Outcome

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Elisabet Ihse; Uppsala universitet.; [2011]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amyloid; transthyretin; familial amyloidotic polyneuropathy; TTRV30M; non-TTRV30M; wild-type; liver transplantation; cardiomyopathy; fibril composition; Biokemi; Biochemistry; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Experimentell patologi; Experimental Pathology; Medical Biochemistry; Medicinsk biokemi; Molecular Biology; Molekylärbiologi; Pathology; Patologi;

    Sammanfattning : Systemic amyloidoses are a group of lethal diseases where proteins aggregate into fibrillar structures, called amyloid fibrils, that deposits throughout the body. Transthyretin (TTR) causes one type of amyloidosis, in which the aggregates mainly infiltrate nervous and cardiac tissue. LÄS MER