Sökning: "Ian Nicholls"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden Ian Nicholls.

1. 1. Novel strategies for C-C/X bond formation

   Författare :Prasad Anaspure; Ian A. Nicholls; Suppan Kathiravan; Jesper G. Wiklander; Subramanian Suriyanarayanan; Yannick Landais; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; annulation; C-H activation; heterocycles; heterogeneous catalysis; homogeneous catalysis; lab-on-a-chip; Suzuki cross-coupling; Organic Chemistry; Organisk kemi;

   Sammanfattning : The formation of C-C/X bonds is essential for the manufacture of a broad range of chemicals and materials used in areas critical for maintaining quality of life in modern society, e.g. pharmaceuticals, agrochemicals and polymers, and for aspects of research in organic chemistry. LÄS MER

3. 2. Towards the Rational Design of Molecularly Imprinted Polymers

   Författare :Håkan S Andersson; Ann-Christin Koch-Schmidt; Ian A Nicholls; Klaus Mosbach; Richard F Venn; Tillämpad biokemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Thermodynamics; Molecular Recognition; Polyvalency; Cooperativity; Electrostatic Interactions; Hydrophobic Effect; Chromatography; Frontal Analysis; HPLC; Spectroscopy; Molecularly Imprinted Polymer; Molecular Imprinting; Crown Ether; Template Polymerisation; Cyclodextrin; Biochemistry; Metabolism; Biokemi; Biotechnology; Bioteknik; molecular recognition; Biokemi;

   Sammanfattning : Molecular imprinting is a technique by which polymeric materials selective for a given target molecule can be created through a casting procedure. Functionalised monomers are added to a solution of molecular templates. LÄS MER

4. 3. Towards new computational tools for predicting toxicity

   Författare :Swapnil Chavan; Ian Nicholls; Scott Boyer; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Acute toxicity; chronic toxicity; hERG; k-NN; LD50; LOEL; Munro database; QSAR; read-across; toxicity; Medicinsk kemi; Medical Chemistry;

   Sammanfattning : The toxicological screening of the numerous chemicals that we are exposed to requires significant cost and the use of animals. Accordingly, more efficient methods for the evaluation of toxicity are required to reduce cost and the number of animals used. LÄS MER

5. 4. Signal Enhancement by Dynamic Polymers in Quartz Crystal Microbalance Applications

   Författare :Gunnar Dunér; Olof Ramström; Ian Nicholls; Andra Dedinaite; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Signal enhancement; QCM; polyelectrolytes; hydrogel; iniferter; photopolymerization; dynamic polymers; Chemistry; Kemi;

   Sammanfattning :  This licentiate thesis presents studies of signal enhancement by dynamic polymers in quartz crystal microbalance (QCM) applications. The aim of the study has been to determine the potential for the use of polymers on QCM sensors for signal enhancement in molecular interaction studies. LÄS MER

7. 5. QCM-based sensing using biological and biomimetic interfaces

   Författare :Louise Elmlund; Ian Nicholls; Teodor Aastrup; Jesper Wiklander; Kristina Nilsson-Ekdahl; Håkan Andersson; Susanne Wikman; Alessandra Maria Bossi; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Quartz crystal microbalance; molecularly imprinted polymers; phage display; interactions; artificial receptors; recognition; selectivity; Kemi; Chemistry;

   Sammanfattning : The objective of this thesis was to explore novel approaches for studying molecular recognition at biological and biomimetic surfaces using the quartz crystal microbalance (QCM) biosensor technique. The first two papers focused on the synthesis and study of biotin selective polymer films prepared using the molecularly imprinted polymer (MIP) technique. LÄS MER