Sökning: "Lund Neurologi"

Visar resultat 16 - 20 av 127 avhandlingar innehållade orden Lund Neurologi.

  1. 16. Functional Recovery after Experimental Stroke in Mice- Involvement of Enriched Environment, BDNF and Cell Genesis

    Författare :Josefine Nygren; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; neurofysiologi; neurophysiology; Neurologi; Neurology; neuropsychology; functional recovery; focal ischemia; cell genesis; BDNF; enriched environment; mice;

    Sammanfattning : Stroke is caused by an obstruction of blood flow to a part of the brain, resulting in brain damage. Stroke is the third most common cause of death in the industrialized world, and the primary cause of adult-onset disability. LÄS MER

  2. 17. Mechanisms of Ischemic Brain Injury- studies in murine hippocampal slice cultures

    Författare :Anna Rytter; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurophysiology; Neurologi; neuropsykologi; neuropsychology; Neurology; adenosine; caspases; hypothermia; in vitro; hippocampus; ischemia; neurofysiologi;

    Sammanfattning : Cerebral ischemia is a major cause of mortality and morbidity in the western world. Even though much effort has been put into research and development of effective drugs against ischemic damage there is to date no effective pharmacological brain protective treatment. LÄS MER

  3. 18. Post-Ischemic Housing Conditions Influence On Gene Transcription And Translation After Permanent Focal Brain Ischemia In Rats

    Författare :Li-Ru Zhao; Sektion IV; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rats; brain-derived neurotrophic factor; mRNA; nerve growth factor-induced gene A; corticosteroid receptors; in situ hybridization; Neurologi; neurophysiology; Neurology; neuropsychology; brain ischemia; enriched environment; neuropsykologi; neurofysiologi;

    Sammanfattning : Enriched environment (EE) housing significantly ameliorates neurological deficits induced by cortical brain ischemia without changing infarction size, suggesting that EE-related functional benefits are associated with neuronal plasticity events in the remaining tissue. Brain-derived neurotrophic factor (BDNF), nerve growth factor-induced gene A (NGFI-A) and corticosteroid receptors (mineralocorticoid receptor, MR; glucocorticoid receptor, GR) have been demonstrated to be involved in brain plasticity. LÄS MER

  4. 19. Clincal Aspects of Biological Brain Damage Markers

    Författare :Johan Undén; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarkers markers; traumatologi; Neurology; Kirurgi; ortopedi; orthopaedics; traumatology; Surgery; intensivvård; Anestesiologi; intensive care; hematoma haematoma; Anaesthesiology; epidural; extracerebral; neurointensive care; head injury; stroke; APC APC-PCI; GFAP; NSE; S100 S-100 S100B S100BB; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi; brain damage injury; serum;

    Sammanfattning : Biomarkers for organ damage and/or dysfuntion are used in almost all areas of medicine. The brain has eluded this technological development for some time. Recently, the S100B protein has been shown to be a promising marker of brain damage. However, before S100S can reach clinical reality, several problems must be solved. LÄS MER

  5. 20. Brain Tumor Imaging and Treatment Effects. Imaging findings and cognitive function in glioblastoma patients

    Författare :Anna Rydelius; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma; Imaging finding; Quantitative volumetry; Cognitive function; Diffusion tensor imaging DTI ; Treatment effect; Radiotherapy; VMAT; Parametric response maps PRM ; Treatment responce prediction;

    Sammanfattning : AbstractBackground: Glioblastoma is the most common malignant brain tumor. Operation with maximal resection, if feasible, otherwise biopsy followed by radiotherapy and chemotherapy with temozolomide is standard therapy. The prognosis remains poor, with median overall survival being 15 months despite therapy. LÄS MER