Avancerad sökning
Visar resultat 1 - 5 av 127 avhandlingar som matchar ovanstående sökkriterier.
1. A population-based study on neuropsychological and morphological signs of idiopathic normal pressure hydrocephalus
Sammanfattning : BACKGROUND: Idiopathic normal pressure hydrocephalus (iNPH) is typically manifested in people over 65 years. The condition of gait disturbances, incontinence, and cognitive dysfunction can be reversed in up to 80% of the cases by ventricular shunting. LÄS MER
2. Stroke epidemiology in Southern Sweden. Trends in incidence and survival across two decades with projections into the future
Sammanfattning : Background: Stroke is a major cause of death and disability. Investigations of the epidemiological trends for stroke might result in better understanding of stroke pathogenesis and prevention. LÄS MER
3. Experimental Stroke and Neurotrophins: Regulation, function and gene transfer of neurotrophins in rat and mouse models of focal cerebral ischemia
Sammanfattning : Stroke caused by focal cerebral ischemia is a major cause of death and neurological disability in humans. The forebrain region most commonly affected by ischemic incidents is that supplied by the middle cerebral artery. LÄS MER
4. Neuroprotection and neurogenesis after experimental stroke
Sammanfattning : In this thesis, two potential endogenous mechanisms for neuronal survival and repair have been investigated in a rat model of stroke, middle cerebral artery occlusion (MCAO): signaling of the GDNF family of neurotrophic factors, and neurogenesis from endogenous progenitor cells. As determined by in situ hybridization for GDNF family ligand and receptor genes, MCAO caused widespread upregulation of both components of the functional GDNF receptor, c-Ret and GFRalpha1, indicating that GDNF may be a survival signal in stroke. LÄS MER
5. Multiple Sclerosis: Studies of the Interferon system and search for infectious agents
Sammanfattning : Multiple sclerosis (MS) is a chronic disease of the central nervous system, characterized by focal inflammatory lesions with demyelination and axonal loss. It is believed that MS is an immune-mediated disorder with both genetic and environmental contributions to the pathogenesis. LÄS MER