Sökning: "caspases"

Visar resultat 1 - 5 av 76 avhandlingar innehållade ordet caspases.

  1. 1. Neuroinflammation in Alzheimer's disease Focus on NF-κB and C/EBP transcription factors

    Detta är en avhandling från Stockholm : Department of Neurochemistry, Stockholm University

    Författare :Veronica Ramberg; Kerstin Iverfeldt; Josep Saura; [2011]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Alzheimer’s disease; neuroinflammation; NF-κB; C EBP; apoptosis; caspases; FRET; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Sammanfattning : Alzheimer's disease (AD) is the most common form of dementia among elderly. The disease is characterized by amyloid-β (Aβ) plaques, neurofibrillary tangles, loss of synapses and neurons and chronic neuroinflammation. LÄS MER

  2. 2. Novel Interactors of X-linked Inhibitor of Apoptosis Protein Expression and Effects on Tumor Cell Death

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Håkan Steen; Dan Lindholm; Bertrand Joseph; [2008]
    Nyckelord :Neurobiology; XIAP; tumor cell death; apoptosis; caspases; basic helix-loop-helix protein; Neurobiologi;

    Sammanfattning : Programmed cell death, or apoptosis, has during the last decade received a lot of attention due to its involvement in a large number of pathological conditions. Since death is always irreversible, it is important for cells to fully control the initiation and execution of this process. LÄS MER

  3. 3. Regulation of neutrophil apoptosis

    Detta är en avhandling från Maria Alvarado-Kristensson, experimentall pathology, Lund University, U-MAS, entrance 78, 205 02 Malmö

    Författare :Maria Alvarado-Kristensson; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; General pathology; pathological anatomy; Patologi allmän ; patologisk anatomi; PP2A; p38 MAPK; caspases; signal transduction; inflammation; Apoptosis; human neutrophils;

    Sammanfattning : The human neutrophil is the most abundant granulocyte and the major type of cell involved in an acute inflammatory response. Neutrophils are armed with various systems of enzymes, that can find and kill pathogens, but unfortunately, these "weapons" cannot distinguish between the host tissues and the "invaders. LÄS MER

  4. 4. Experimental radioimmunotherapy and effector mechanisms

    Detta är en avhandling från Umeå : Klinisk mikrobiologi

    Författare :David Eriksson; Torgny Stigbrand; Eva Forsell-Aronsson; [2006]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; radioimmunotherapy; apoptosis; mitotic catastrophe; caspases; cell cycle disturbances; combination treatment.; NATURAL SCIENCES Biology Cell and molecular biology Immunology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Immunologi;

    Sammanfattning : Radioimmunotherapy is becoming important as a new therapeutic strategy for treatment of tumour diseases. Lately monoclonal antibodies tagged with radionuclides have demonstrated encouraging results in treatment of hematological malignancies. The progress in treatment of solid tumours using radioimmunotherapy, however, has been slow. LÄS MER

  5. 5. Mechanisms of Ischemic Brain Injury- studies in murine hippocampal slice cultures

    Detta är en avhandling från Anna Rytter, Laboratory for Experimental Brain Research

    Författare :Anna Rytter; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurophysiology; Neurologi; neuropsykologi; neuropsychology; Neurology; adenosine; caspases; hypothermia; in vitro; hippocampus; ischemia; neurofysiologi;

    Sammanfattning : Cerebral ischemia is a major cause of mortality and morbidity in the western world. Even though much effort has been put into research and development of effective drugs against ischemic damage there is to date no effective pharmacological brain protective treatment. LÄS MER