Sökning: "GABA"

Visar resultat 16 - 20 av 149 avhandlingar innehållade ordet GABA.

  1. 16. Neurotransmission and functional synaptic plasticity in the rat medial preoptic nucleus

    Författare :Evgenya Malinina; Staffan Johansson; Eric Hanse; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; medial preoptic nucleus; synaptic plasticity; GABA; glutamate; L-type Ca2 channel; Physiology; Fysiologi; fysiologi; Physiology;

    Sammanfattning : Brain function implies complex information processing in neuronal circuits, critically dependent on the molecular machinery that enables signal transmission across synaptic contacts between neurons. The types of ion channels and receptors in the neuronal membranes vary with neuron types and brain regions and determine whether neuronal responses will be excitatory or inhibitory and often allow for functional synaptic plasticity which is thought to be the basis for much of the adaptability of the nervous system and for our ability to learn and store memories. LÄS MER

  2. 17. Neurogenesis in the adult brain from ballyhoo to sobriety

    Författare :Helena Frielingsdorf; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; neurofysiologi; Neurologi; neurophysiology; neuropsychology; Neurology; Nerve growth factor; acetylcholine; GABA; learning; hippocampus; Neurogenesis; dopamine; substantia nigra;

    Sammanfattning : New neurons are spontaneously generated in two regions of the adult brain, the hippocampus and the subventricular zone/olfactory bulb. The objective of this thesis was to study potential implications for adult neurogenesis in Alzheimer's (AD) and Parkinson's diseases (PD). LÄS MER

  3. 18. Regulation of insulin producing cells, stress responses and metabolism in Drosophila

    Författare :Neval Kapan; Dick R. Nässel; Alberto Ferrus; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Insulin signaling; Drosophila melanogaster; peptide hormones; neuropeptides; GABA; funktionell zoomorfologi; Functional Zoomorphology;

    Sammanfattning : In Drosophila, neuropeptides have regulatory roles in development, growth, metabolism and reproduction. This study focused on GABA and the neuropeptides Drosophila tachykinin (DTK), short neuropeptide F (sNPF), adipokinetic hormone (AKH), corazonin (CRZ) and Drosophila insulin-like peptides (DILPs) as possible regulators of metabolic stress responses and homeostasis. LÄS MER

  4. 19. Allopregnanolone effects on food intake and weight gain

    Författare :Ellinor Holmberg; Torbjörn Bäckström; Bo Söderpalm; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allopregnanolone; neurosteroid; GABA; GABAA receptor; food intake; weight gain; obesity; hyperphagia; diurnal rhythm; schedule feeding; high fat diet; electrophysiology; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Background Obesity is currently one of the major causes of ill health and it is clear that overeatingis the cause of obesity. However, the actions of many endogenous factors that contribute to overeating are still not well understood. LÄS MER

  5. 20. Taste Hedonics and the Intake of Alcohol and Food

    Författare :Anna Söderpalm; Göteborgs universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Alcohol drinking; Adrenalectomy; Corticosterone; Cyanoketone; Food intake; Food restriction; GABA; Metyrapone; Taste reactivity; Benzodiazepine; Chlordiazepoxide; Cis Z -flupentixol; Diazepam; Flumazenil; Microinjections; Midazolam; Nucleus of the Solitary tract; Palatability; Parabrachial nucleus; Peduculopontine Tegmental Nucleus; Reward; 4th ventricle.;

    Sammanfattning : This thesis includes four papers based on animal experimental work. They analyze the way in which activation of a specific motivational state - hunger- modulates the rewarding actions of alcohol and taste palatability. LÄS MER