Sökning: "GABA"

Visar resultat 21 - 25 av 149 avhandlingar innehållade ordet GABA.

  1. 21. Enhancing neuronal inhibition by cell and gene therapy as a novel treatment for Epilepsy

    Författare :Ana Gonzalez Ramos; Epilepsicentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epilepsy; Interneurons; GABA; Human pluripotent stem cells; Cell therapy; Gene therapy; Chemogenetics; Hippocampus; TLE; Cntnap2;

    Sammanfattning : Epilepsy is a family of heterogeneous and multifactorial neurological disorders, unified by the occurrence of spontaneous recurrent seizures. Overall, it affects 50 million people worldwide of all ages and genders. LÄS MER

  3. 22. Ocular function and morphology in humans and rabbits exposed to vigabatrin medication

    Författare :Ulrika Kjellström; Lund Oftalmologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vimentin; PKC-alpha; visual field defects; optical coherence tomography; full-field electroretinography; GABA; vigabatrin;

    Sammanfattning : Vigabatrin is an antiepileptic drug that is known to cause visual field defects and retinal dysfunction measured by full-field electroretinography (ff-ERG). Underlying mechanisms have not yet been elucidated. LÄS MER

  4. 23. Cyanide and central nervous system : a study with focus on brain dopamine

    Författare :Gudrun Cassel; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CNS; cyanide; dopaminergic system; convulsions; receptor binding; tyrosine hydroxylase; monoamine oxidase; extracellular release; inositol phosphate; GABA; GAD;

    Sammanfattning : The brain is a major target site in acute cyanide intoxication, as indicated by several symptoms and signs. Cyanide inhibits the enzyme cytochrome oxidase. This inhibition causes impaired oxygen utilization in all cells affected, severe metabolic acidosis and inhibited production of energy. LÄS MER

  5. 24. Allopregnanolone and mood : studies of postmenopausal women during treatment with progesterone

    Författare :Lotta Andréen; Torbjörn Bäckström; Viveca Odlind; Umeå universitet; []
    Nyckelord :Obstetrics and gynaecology; Progesterone; Allopregnanolone; GABA; mood; bimodal; Obstetrik och kvinnosjukdomar;

    Sammanfattning : Introduction. Allopregnanolone and pregnanolone (neuroactive metabolites of progesterone) act as positive modulators of the GABAA receptor system which is the major inhibitory system in CNS. Contradictory results on the effect of GABAA receptor modulators are reported. LÄS MER

  7. 25. Applications of nanospray desorption electrospray ionization mass spectrome : Analysis of lipids and metabolites in brain tissue sections and single cells

    Författare :Hilde-Marléne Bergman; Ingela Lanekoff; Jonas Bergquist; Leopold Ilag; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nano-DESI; single cell analysis; small molecule neurotransmitters; mass spectrometry imaging; MSI; GABA; Glutamate; Acetylcholine; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

    Sammanfattning : .... LÄS MER