Sökning: "glutamate"

Visar resultat 1 - 5 av 309 avhandlingar innehållade ordet glutamate.

  1. 1. Early life experiences and alcohol use in youth : An emerging role of the Vesicular Glutamate Transporters

    Författare :Maria Vrettou; Erika Comasco; Ingrid Nylander; Kent W. Nilsson; Åsa Wallén-Mackenzie; Roberto Ciccocioppo; Uppsala universitet; []
    Nyckelord :alcohol; early-life stress; brain; early adulthood; expression; DNA methylation; glutamate; Vesicular Glutamate Transporters;

    Sammanfattning : Initiation of alcohol consumption usually takes place during adolescence, a period characterized by a plethora of physical and emotional changes. Towards early adulthood, hazardous drinking patterns can emerge and potentially lead to the development of Alcohol Use Disorder (AUD). LÄS MER

  2. 2. Glutamate for metabolic intervention in coronary surgery : with special reference to the GLUTAMICS-trial

    Författare :Mårten Vidlund; Rolf Svedjeholm; Torbjörn Ivert; Örebro universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; myocardial ischemia; coronary artery bypass; cardiac surgery; acute coronary syndrome; glutamate; metabolic intervention; postoperative heart failure; myocardial recovery; Surgery; Kirurgi;

    Sammanfattning : Myocardial ischemia is a major cause of postoperative heart failure and adverse outcome in coronary artery bypass graft surgery (CABG). Conventional treatment of postoperative heart failure with inotropic drugs may aggravate underlying ischemic injury. LÄS MER

  3. 3. Glutamate Turnover and Energy Metabolism in Brain Injury : Clinical and Experimental Studies

    Författare :Carolina Samuelsson; Elisabeth Ronne-Engström; Lars Hillered; Eva Kumlien; Carl-Henrik Nordström; Uppsala universitet; []
    Nyckelord :Neurosciences; glutamate; glutamine; lactate; pyruvate; microdialysis; GLT-1; energy metabolism; intracranial pressure; cerebral perfusion pressure; subarachnoid hemorrhage; ischemia; epilepsy; Neurovetenskap;

    Sammanfattning : During brain activity neurons release the major excitatory transmitter glutamate, which is taken up by astrocytes and converted to glutamine. Glutamine returns to neurons for re-conversion to glutamate. This glutamate-glutamine cycle is energy demanding. LÄS MER

  4. 4. Plasticity of the developing glutamate synapse in the hippocampus

    Författare :Therése Abrahamsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :synaptic plasticity; long-term potentiation; short-term potentiation; silent synapse; development; hippocampus; glutamate;

    Sammanfattning : Synapses are highly plastic, i.e. they have the ability to change their signaling strength both in the short- and long-term (e.g. LÄS MER

  5. 5. Creating Ultrafast Biosensors for Neuroscience

    Författare :Yuanmo Wang; Chalmers University of Technology; []
    Nyckelord :NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; quantification; glucose; choline oxidase; gold nanoparticles; enzyme monolayer; enzymatic activity; Biosensor; adsorption; brain slice; enzyme stability; acetylcholine esterase; artificial cell; exocytosis; glucose oxidase; deformation; glutamate; glutamate oxidase; acetylcholine; amperometry;

    Sammanfattning : Neuronal communication is the basis for all our brain function and relies on regulated exocytosis, a cell function that involves release of quantal amounts of neurotransmitters into the gap space between interconnected neurons to serve as chemical signals. To study exocytosis, which is a fast process that occurs on the timescale of sub-milliseconds to milliseconds, a toolbox of analytical methods has been developed where the electrochemical based techniques offer quantitative and sufficient high temporal recording speed. LÄS MER