Sökning: "Effective population size"

Visar resultat 21 - 25 av 93 avhandlingar innehållade orden Effective population size.

1. 21. Palaeogenomic reconstruction of woolly mammoth evolutionary history and extinction dynamics

   Författare :Marianne Dehasque; Love Dalén; David Díez-del-Molino; Rike Stelkens; Rebecca N. Johnson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; woolly mammoth; Mammuthus primigenius; extinction; Wrangel Island; ancient DNA; palaeogenomics; radiocarbon dating; structural variants; genome erosion; population structure; Systematic Zoology; zoologisk systematik och evolutionsforskning;

   Sammanfattning : Biodiversity is declining globally. Yet, the biological and genetic processes associated with these declines on a longer timescale are still poorly understood. Ancient DNA is a powerful tool to study evolution in real-time. Despite advances in the field, there is further need for refinement of laboratory and computational techniques. LÄS MER

3. 22. Population genomic analyses of regulatory variation and selection in Brassicaceae species

   Författare :Robert Horvath; Tanja Slotte; Peter Hambäck; Douglas G. Scofield; Matthew Webster; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Capsella grandiflora; Arabidopsis thaliana; Arabidopsis lyrata; natural selection; gene expression variation; DNA and gene body methylation; transposable elements; DNA accessibility; gene expression noise; epigenetic silencing; linked selection; ekologi och evolution; Ecology and Evolution;

   Sammanfattning : The impact of selection on regulatory variation and the contribution of regulatory changes to phenotypic variation has long been debated in evolutionary genetics. Because cis-regulatory elements such as promoters and enhancers can be difficult to identify, it has been more challenging to quantify the impact of selection on variation in cis-regulatory regions than in protein-coding regions. LÄS MER

4. 23. Fisheries biology of the edible crab (Cancer pagurus) in the Kattegat and the Skagerrak - implications for sustainable management

   Författare :Anette Ungfors; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cancer pagurus; Swedish west coast; sexual maturity; migration; population genetics; stock structure; fishing mortality; stock abundance; management;

   Sammanfattning : The European edible crab (Cancer pagurus) is exploited to a varying degree in its area of distribution. Landings in United Kingdom and Ireland may have peaked around year 2000, reaching 25 000 and 13 000 tonnes, respectively but have slightly decreased since. LÄS MER

5. 24. Untangling Cortico-Striatal Circuitry and its Role in Health and Disease - A computational investigation

   Författare :Jovana Belic; Jeanette Hellgren Kotaleski; Arvind Kumar; Abigail Morrison; Arthur Leblois; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cortico-striatal circuits; levodopa-induced dyskinesia; Parkinson’s disease; effective connectivity; cross-frequency coupling; corticostriatal network; network oscillations; GABAergic transmission. basal ganglia; striatum; cortex; fast spiking interneurons; medium spiny neurons; neuronal avalanches;

   Sammanfattning : The basal ganglia (BG) play a critical role in a variety of regular motor and cognitive functions. Many brain diseases, such as Parkinson’s diseases, Huntington’s disease and dyskinesia, are directly related to malfunctions of the BG nuclei. LÄS MER

7. 25. Leg ulcer management in primary care with special reference to pinch grafting

   Författare :Rut Öien; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatology locomotion; Skelett; muskelsystem; reumatologi; General practice; medical training; Allmän medicinsk utövning; medicinsk utbildning; muscle system; Skeleton; diameter product; grid tracing; digital planimetry; ulcer size; pain relief; vasculitis; rheumatoid arthritis; cost analysis; healing rate; pinch grafting; aetiology; prevalence; Leg ulcer; primary care;

   Sammanfattning : Wound management in primary and community care was investigated throughout a period of 12 years within a well-defined population in one county in Southern Sweden. The estimated prevalence of chronic leg and foot ulcers was 0.19% in 1998 and the mean prevalence was 0.20% during the years 1994-1998. LÄS MER