Sökning: "cortex"

Visar resultat 1 - 5 av 609 avhandlingar innehållade ordet cortex.

  1. 1. On the role of penicillin-binding protein SpoVD in endospore cortex assembly

    Författare :Ewa Bukowska-Faniband; Molekylär cellbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; sporulation; cortex; Bacillus subtilis; penicillin-binding proteins; SpoVD; peptidoglycan;

    Sammanfattning : Bacteria of the genera Bacillus and Clostridium can form endospores as a strategy to survive unfavourable environmental conditions. Endospore formation involves synthesis of cortex, a thick layer of modified peptidoglycan that surrounds the spore. LÄS MER

  2. 2. Towards Cortex Isomorphic Attractor Neural Networks

    Författare :Christopher Johansson; KTH; []
    Nyckelord :Attractor Neural Networks; Cerebral Cortex; Minicolumns; Hypercolumns; Potts Neural Networks; BCPNN; and Parallel Computers;

    Sammanfattning : In this thesis we model the mammalian cerebral cortex withattractor neural networks and study the parallelimplementations of these models. First, we review the size, structure, and scaling laws ofthe cerebral cortex of five mammals; mouse, rat, cat, macaque,and human. LÄS MER

  3. 3. Untangling Cortico-Striatal Circuitry and its Role in Health and Disease - A computational investigation

    Författare :Jovana Belic; Jeanette Hellgren Kotaleski; Arvind Kumar; Abigail Morrison; Arthur Leblois; KTH; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cortico-striatal circuits; levodopa-induced dyskinesia; Parkinson’s disease; effective connectivity; cross-frequency coupling; corticostriatal network; network oscillations; GABAergic transmission. basal ganglia; striatum; cortex; fast spiking interneurons; medium spiny neurons; neuronal avalanches;

    Sammanfattning : The basal ganglia (BG) play a critical role in a variety of regular motor and cognitive functions. Many brain diseases, such as Parkinson’s diseases, Huntington’s disease and dyskinesia, are directly related to malfunctions of the BG nuclei. LÄS MER

  4. 4. Segmentation and Visualisation of Human Brain Structures

    Författare :Roger Hult; Ewert Bengtsson; Lennart Thurfjell; Håkan Hall; Ingrid Agartz; Arvid Lundervold; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Bildanalys; segmentation; visualisation; brain; cortex; hippocampus; autoradiography; MRI; PET; ROI; Bildanalys; Image analysis; Bildanalys; Computerized Image Analysis; datoriserad bildanalys;

    Sammanfattning : In this thesis the focus is mainly on the development of segmentation techniques for human brain structures and of the visualisation of such structures. The images of the brain are both anatomical images (magnet resonance imaging (MRI) and autoradigraphy) and functional images that show blood flow (functional magnetic imaging (fMRI), positron emission tomography (PET), and single photon emission tomograpy (SPECT)). LÄS MER

  5. 5. Generation of cortical neurons through reprogramming technology

    Författare :Giedre Miskinyte; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; Cortex; Reprogramming; human ES cells; transcription factor programming; cortical projection neurons; Human adult cortical slices;

    Sammanfattning : The human cortex is affected by several debilitating acute and chronic neurodegenerative disorders such as stroke, traumatic brain injury, amyotrophic lateral sclerosis and Alzheimer’s disease, which target specific types of cortical neurons. Emerging evidence indicates that stem cells and reprogrammed cells can be used to generate human cortical neurons both for cell replacement by transplantation, and for disease modeling and drug screening. LÄS MER