Sökning: "gene expression variation"
Visar resultat 1 - 5 av 285 avhandlingar innehållade orden gene expression variation.
1. Gene Expression in Cancer Cells : Detection of Splice Variants, Allele-specific Expression and DNA Methylation
Sammanfattning : The human genome sequencing project has provided a wealth of information on sequence variation between individuals. The surprisingly low number of genes in the human genome is compensated for by a complex regulation of gene expression. LÄS MER
2. Population genomic analyses of regulatory variation and selection in Brassicaceae species
Sammanfattning : The impact of selection on regulatory variation and the contribution of regulatory changes to phenotypic variation has long been debated in evolutionary genetics. Because cis-regulatory elements such as promoters and enhancers can be difficult to identify, it has been more challenging to quantify the impact of selection on variation in cis-regulatory regions than in protein-coding regions. LÄS MER
3. Sexual Conflict and Gene Expression in Drosophila melanogaster
Sammanfattning : Sexual conflict is broadly defined as a conflict between the evolutionary interests of the two sexes. Depending on the genetic architecture of the traits involved, it can occur at the level of male-female interactions or take the form of selection acting to change the mean of a shared trait against the sign of its genetic correlation. LÄS MER
4. MHC diversity and expression in a songbird : Temporal and transgenerational variation
Sammanfattning : The immune system is of central importance to clear-off pathogens in order to keep an organism healthy. In vertebrates, the Major Histocompatibility Complex (MHC) is a genomic region that holds key genes involved in adaptive immunity and in particular in the antigen presenting process. LÄS MER
5. Intrinsic disorder and tandem repeats - match made in evolution : Computational studies of molecular evolution
Sammanfattning : Proteins are both the building blocks and workers of the cell, carrying out most of the important functions. For a long time, their structure has been regarded as the primary factor for their function, but intrinsically disordered proteins demonstrate an alternative to this paradigm. LÄS MER