Sökning: "population genetics"

Visar resultat 1 - 5 av 426 avhandlingar innehållade orden population genetics.

  1. 1. Complex disease genetics Utilising targeted sequencing and homogeneous ancestry

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Argyri Mathioudaki; Uppsala universitet.; [2019]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ankylosing spondylitis; breast cancer; targeted sequencing; Sweden; genetics; population stratification.; Molekylär genetik; Molecular Genetics;

    Sammanfattning : The complex disease investigations presented in this thesis aimed to provide new information regarding underlying genetics by using targeted sequencing and ethnically homogeneous cohorts. This work moved past current methodologies and addressed data stratification issues, that might have been hindering new findings. LÄS MER

  2. 2. Population Genetics of Human Genomic Elements

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Thijessen Naidoo; Uppsala universitet.; [2018]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; population genetics; human genome; functional elements; natural selection; pseudogenes; loss-of-function; gene regulation; Y chromosome; Biology with Specialisation in Human Evolution and Genetics; Biologi med inriktning mot människans evolution och genetik;

    Sammanfattning : The genomes of living organisms are composed of a multitude of functional units, which interact with each other and their environment in a highly regulated fashion, to facilitate the expression of an enduring (and evolving) phenotype. Several approaches have emerged in the effort to identify these functional units and explore their activities. LÄS MER

  3. 3. Complex Trait Genetics Beyond Additivity

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Simon Forsberg; Uppsala universitet.; [2016]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; genetic interactions; epistasis; additivity; GWAS; vGWAS; Genetic mapping; yeast; Arabidopsis Thaliana; dog; Genetics; Genetik;

    Sammanfattning : The link between the genotype and the phenotype of an organism is immensely complex. Despite this it can, to a great extent, be captured using models that assume that gene variants combine their effects in an additive manner. This thesis explores aspects of genetics that cannot be fully captured using such additive models. LÄS MER

  4. 4. Molecular population genetics of inducible defense genes in Populus tremula

    Detta är en avhandling från Umeå : Umeå Universitet

    Författare :Carolina Bernhardsson; Umeå universitet.; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Populus; herbivore defense; adaptation; population genetics; population structure; association mapping; complex traits; evolutionär genetik; evolutionär genetik;

    Sammanfattning : Plant-herbivore interactions are among the most common of ecological interactions. It is therefore not surprising that plants have evolved multiple mechanisms to defend themselves, using both constitutive chemical and physical barriers and by induced responses which are only expressed after herbivory has occurred. LÄS MER

  5. 5. Sexuality, apomixis and polyploidy; Potentilla argentea as a critical example

    Detta är en avhandling från Genetics

    Författare :Svante Holm; [1996]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; flow cytometry; RAPD; isozyme; crossings; population; Potentilla argentea; clonal; reproduction; Sexuality; apomixis; Genetics; cytogenetics; Genetik; cytogenetik;

    Sammanfattning : Finding a diploid facultative apomictic plant species would give a great opportunity to solve problems concerning the existence and persistence of sexuality and also, it would be a possible source to get a transferable apomictic gene from. The putative diploid facultative apomict Potentilla argentea from southern Sweden was investigated with RAPD, isozymes and flow cytometry. LÄS MER