Sökning: "chondrocyte"

Visar resultat 1 - 5 av 40 avhandlingar innehållade ordet chondrocyte.

  1. 1. Studies on chondrocyte integrins and mechanical signaling

    Författare :Karin Holmvall; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; teratology; Development biology; collagen; mechnaical stimulation; cartilage; development; chondrocyte; integrin; ontogeny; embryology human ; Utvecklingsbiologi; teratologi; embryologi människa ;

    Sammanfattning : Integrins are a family of cell surface receptors known to bind matrix proteins and to mediate signals such as mechanical signals between the cell and the surrounding matrix. We have studied integrins that are expressed by chondrocytes, with specific focus on the integrins that interact with the cartilage matrix protein collagen type II. LÄS MER

  2. 2. Chondrocyte-matrix interactions: with emphasis on the collagen binding integrin a10ß1

    Detta är en avhandling från Dept. for Cell and Molecular Biology, P.O Box 94, S-22100 Lund

    Författare :Lisbet Camper; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscle system; Skeleton; chondrocyte; integrin; cartilage; chondroadherin; collagen; Biochemistry; metabolism; Biokemi; reumatologi; muskelsystem; Skelett; rheumatology locomotion;

    Sammanfattning : The work in this thesis has been focused on chondrocyte integrins and their interaction with the matrix proteins chondroadherin (CHAD) and collagen type II (CII). Affinity purification of CHAD-binding proteins from chondrocyte lysate, followed by immunoprecipitation of EDTA-eluted material identified alpha2beta1 as a CHAD-binding integrin. LÄS MER

  3. 3. Functional analysis of the alpha10beta1 integrin

    Detta är en avhandling från Therese Bengtsson (Cartela AB) or from library

    Författare :Therese Bengtsson; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cytogenetics; Genetik; cytogenetik; limb; gene targeting; chondrocyte; integrin; cartilage;

    Sammanfattning : The aim of this thesis was to study the function of the integrin a10b1. Integrins mediate signals between cells and their environment and regulate several cellular processes such as cell migration, proliferation and differentiation. LÄS MER

  4. 4. Studies on various culture systems for chondrocytes and osteoblasts

    Detta är en avhandling från Umeå : Umeå University

    Författare :Juha Prittinen; Mikko Lammi; Minna Kellomäki; [2017]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; chondrocyte; osteoarthritis; surface materials; topography; tissue engineering; mechanical stimulation; Medical Cell Biology; medicinsk cellbiologi;

    Sammanfattning : Osteoarthritis and osteochondral defects are ailments that are increasing in frequency as the lifespan of the population increases and sedentary lifestyle becomes more common. Osteoarthritis is an inflammatory disease that causes the progressive degeneration of articular surfaces and the underlying bone. LÄS MER

  5. 5. Basement membrane components in the chondrocyte extracellular matrix

    Detta är en avhandling från Lund University: Faculty of Medicine

    Författare :Alexander Kvist; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skelett; rheumatology locomotion; nidogen; chondroitin sulfate; collagen assembly; Skeleton; muscle system; type IV collagen; laminin; perlecan; basement membranes; ECM; chondrcytes; muskelsystem; reumatologi;

    Sammanfattning : The extracellular matrix (ECM) is a network of macromolecules which, together with cells, forms the various tissues of all metazoan organisms. Cartilage, in contrast to most other tissues, contains relatively few cells in proportion to the volume occupied by ECM. LÄS MER