Sökning: "Cellular Differentiation"
Visar resultat 1 - 5 av 430 avhandlingar innehållade orden Cellular Differentiation.
Sammanfattning : This work focus on the functions by which the transcription factor Early B-cell Factor (EBF) regulate gene expression in different cell types. To address this question, gene expression analyses aimed to investigate the regulatory role of EBF in neuroblastoma cells, B-lymphocytes, adipocytes and stromal cells were performed. LÄS MER
Sammanfattning : Neural stem cell self-renewal and differentiation are tightly regulated events during CNS development, leading to cell division into new neural stem cells or the formation of neurons and glial cells. This thesis focuses on the cellular responses induced by known and novel factors in neural stem and progenitor cells (NSPCs). LÄS MER
3. Device Bonding and Antibody Binding: Developments for On-Chip Differentiation of Induced Pluripotent Stem Cells into Hepatocytes
Sammanfattning : Abstract This thesis describes the bonding optimization of a liver-on-a-chip microfluidic device for evaluation of cultured induced pluripotent stem cell (iPSC)-derived definitive endoderm (DE) cells during their targeted differentiation into mature hepatocytes. Furthermore, it describes the optimization of a number of antibody assays for use during said differentiation, for the purpose of studying the cellular phenotype. LÄS MER
Sammanfattning : Smooth muscle cells (SMCs) are a broad class of contractile cells that are found in a number of organs systems, including the vasculature, the urogenital system, the bronchi and the gastrointestinal tract. The two main functions exerted by SMCs are to provide contractile force and to synthesize structural components of the extracellular matrix. LÄS MER
Sammanfattning : Mitochondria from Xenopus laevis and Ambystoma mexica- num embryos between fertilization and the beginning of feeding were studied: the former with respect to metabolic behaviour, enzyme pattern and carrier activity, and the latter with respect to morphological parameters.The metabolic behaviour of mitochondria was studied by assessing the rates of oxygen uptake in presence of various substrates. LÄS MER