Sökning: "Cellular Differentiation"
Visar resultat 11 - 15 av 484 avhandlingar innehållade orden Cellular Differentiation.
11. Characterization of proteins involved in differentiation and apoptosis of human leukemia and epithelial cancer cells
Sammanfattning : Today, cancer is understood as an epigenetic as well as a genetic disease. The main epigenetic hallmarks of the cancer cell are DNA methylation and histone modifications. The latter changes may be an optimal target for novel anticancer agents. LÄS MER
12. The role of PKC in neuronal differentiation and in regulation of the actin cytoskeleton during neurite outgrowth
Sammanfattning : Protein kinase C (PKC) is a family of serine/threonine kinases subgrouped into classical (α, βI, βII, γ), novel (δ, ε, η, θ) and atypical (ζ, ι/λ) isoforms. PKC can be activated by phorbol esters, and prolonged treatment of neuroblastoma cells has been shown to induce neuronal differentiation with neurite outgrowth and increased expression of neuronal genes. LÄS MER
13. Modelling T helper cell activation and development
Sammanfattning : T helper (Th) cell activation and development is one of the most critical events in regulating the adaptive immune response. Understanding its regulation could be of great therapeutical value as many severe diseases are associated with failure in controlling T cell activation and development. LÄS MER
14. C/EBP transcription factors in lung cellular differentiation and development
Sammanfattning : During embryonic development the lung is lined with a primitive epithelium. As development proceeds, the epithelium matures and differentiates into several cell types that together with cells of mesenchymal origin constitute the adult lung. LÄS MER
15. Regulation of cellular architecture in growth, differentiation and transformation : a study on platelet-derived growth factor and src gene products
Sammanfattning : .... LÄS MER