Sökning: "computational prediction"

Visar resultat 1 - 5 av 360 avhandlingar innehållade orden computational prediction.

1. 1. Transmembrane Proteins and Protein Structure Prediction : What we can learn from Computational Methods

   Författare :John Lamb; Arne Elofsson; Paolo Marcatili; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein structure prediction; contact prediction; transmembrane protein; topology prediction; machine learning; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

   Sammanfattning : A protein’s 3D-structure is essential to understand how proteins function and interact and how biochemical processes proceed in organic life. Despite the advancement in experimental methods, it remains expensive and time-consuming to determine protein structure experimentally. LÄS MER

3. 2. Statistical Methods for Computational Markets : Proportional Share Market Prediction and Admission Control

   Författare :Thomas Sandholm; Magnus Boman; Mark Baker; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Distributed Systems; Grid Computing; Performance Analysis; Workload Modeling; Middleware; Quality of Service; Prediction; Admission Control; Computer and systems science; Data- och systemvetenskap;

   Sammanfattning : We design, implement and evaluate statistical methods for managing uncertainty when consuming and provisioning resources in a federated computational market. To enable efficient allocation of resources in this environment, providers need to know consumers' risk preferences, and the expected future demand. LÄS MER

4. 3. Ensemble methods for protein structure prediction

   Författare :Marcin J. Skwark; Arne Elofsson; Michael Tress; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein structure prediction; model quality assessment; contact prediction; homology modeling; ab-initio prediction; consensus prediction; structural bioinformatics; bioinformatics; protein structure; biokemi; inriktning teoretisk kemi; Biochemistry with Emphasis on Theoretical Chemistry;

   Sammanfattning : Proteins play an essential role in virtually all of life's processes. Their function is tightly coupled to the three-dimensional structure they adopt.Solving protein structures experimentally is a complicated, time- and resource-consuming endeavor. LÄS MER

5. 4. Through the coding-lens : community detection and beyond

   Författare :Christopher Blöcker; Martin Rosvall; Juan Carlos Nieves; Jari Saramäki; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; community detection; map equation; Huffman coding; network centrality; link prediction;

   Sammanfattning : We live in a highly-connected world and find networks wherever we look: social networks, public transport networks, telecommunication networks, financial networks, and more. These networks can be immensely complex, comprising potentially millions or even billions of inter-connected objects. LÄS MER

7. 5. Computational Modelling in Drug Discovery : Application of Structure-Based Drug Design, Conformal Prediction and Evaluation of Virtual Screening

   Författare :Martin Lindh; Anders Karlén; Antti Poso; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; drug discovery; docking; virtual screening; tuberculosis; conformal prediction;

   Sammanfattning : Structure-based drug design and virtual screening are areas of computational medicinal chemistry that use 3D models of target proteins. It is important to develop better methods in this field with the aim of increasing the speed and quality of early stage drug discovery. LÄS MER