Sökning: "Medical Biochemistry"
Visar resultat 1 - 5 av 870 avhandlingar innehållade orden Medical Biochemistry.
Sammanfattning : Abstract Sophisticated liposomal systems are emerging at an increasing rate to meet the demands for multifunctional drug carriers in chemotherapies in combined with hyperthermia. For example, liposomal drug carriers for temperature-controlled drug release under hyperthermic conditions have recently been tested in clinical trials. LÄS MER
- Detta är en avhandling från Umeå : Medicinsk kemi och biofysik
Sammanfattning : Ribonucleotide reductase (RNR) is a key enzyme for de novo dNTP biosynthesis. We have studied nucleotide-dependent oligomerization of the allosterically regulated mammalian RNR using a mass spectrometry–related technique called Gas-phase Electrophoretic Mobility Macromolecule Analysis (GEMMA). LÄS MER
3. Studies of Functional Interactions within Yeast Mediator and a Proposed Novel Mechanism for Regulation of Gene ExpressionDetta är en avhandling från Umeå : Medicinsk biokemi och biofysik
Sammanfattning : The yeast Mediator complex is required for transcriptional regulation both in vivo and in vitro and the identification of similar complexes from metazoans indicates that its function is conserved through evolution. Mediator subunit composition and structure is well characterized both by biochemical, genetic and biophysical methods. LÄS MER
- Detta är en avhandling från Umeå : Medicinsk biokemi och biofysik
Sammanfattning : Extracellular matrix degrading proteases from the plasminogen (plg) activator (PA) and the matrix metalloproteinase (MMP) systems have been implicated as important mediators of ovulation and corpus luteum (CL) formation and regression. The aim of this thesis was to investigate the expression and regulation of PAs and MMPs in the ovary and to examine their functional roles for CL formation and function. LÄS MER
- Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis
Sammanfattning : A drastically increased capacity to measure large sets of molecular features in numerous patient samples in great detail will be required to fulfill the vision of precision medicine and wellness, which may characterize molecular diagnostics in the 21st century. Also sampling procedures need a renaissance to permit continuous sampling at population levels at reasonable cost. LÄS MER