Sökning: "Cell adhesion"
Visar resultat 21 - 25 av 630 avhandlingar innehållade orden Cell adhesion.
21. Satellite cells in human skeletal muscle : molecular identification quantification and function
Sammanfattning : Skeletal muscle satellite cells located between the plasma membrane and the basal lamina of muscle fibres, could for many years, only be studied in situ by electron microscopy. The introduction of immunohistochemistry and the discovery of molecular markers of satellite cells then made them accessible for light microscopic studies and a wealth of information is today available. LÄS MER
22. Syndecan - Regulation and Function of its Glycosaminoglycan Chains
Sammanfattning : The cell surface is an active area where extracellular molecules meet their receptors and affect the cellular fate by inducing for example cell proliferation and adhesion. Syndecans and integrins are two transmembrane molecules that have been suggested to fine-tune these activities, possibly in cooperation. Syndecans are proteoglycans, i.e. LÄS MER
23. Cyclin E overexpression and associated events in human breast cancer
Sammanfattning : Unrestrained proliferation is a hallmark of cancer and genetic defects within G1/S-phase regulation and the pRb pathway occur frequently. Proliferation control can be circumvented either by excess cyclin D1 or cyclin E, alterations that can define two alternative tumour biologic pathways in breast cancer. LÄS MER
24. Intestinal Gene Expression Profiling and Fatty Acid Responses to a High-fat Diet
Sammanfattning : The gastrointestinal tract (GIT) regulates nutrient uptake, secretes hormones and has a crucial gut flora and enteric nervous system. Of relevance for these functions are the G protein-coupled receptors (GPCRs) and the solute carriers (SLCs). LÄS MER
25. Endothelial-leukocyte interactions
Sammanfattning : This thesis describes early inflammatory responses involving interactions between leukocytes and the endothelial lining of the blood vessel wall. An adhesion molecule, E-selectin, which is upregulated on interleukin-1 activated endothelium, was found to mediate rolling between leukocytes and endothelial cells in vivo. LÄS MER