Sökning: "Helgi B Schiöth"
Visar resultat 1 - 5 av 18 avhandlingar innehållade orden Helgi B Schiöth.
1. Discovery of novel selective ligands, expression and structural characterisation of the melanocortin receptor subtypes
Sammanfattning : .... LÄS MER
2. The role of HMG-coenzyme A reductase (HMGCR) and statin medication in the Central Nervous System : Cognitive Functions, Metabolism, Feeding and Sleep Behaviour
Sammanfattning : Millions of people are currently on statin medications (HMGCR inhibitors) to prevent cardiovascular diseases. Despite considerable central nervous system expression, little is known about HMGCR function in the brain. LÄS MER
3. Membrane-bound proteins : Characterization, evolution, and functional analysis
Sammanfattning : Alpha-helical transmembrane proteins are important components of many essential cell processes including signal transduction, transport of molecules across membranes, protein and membrane trafficking, and structural and adhesion activities, amongst others. Their involvement in critical networks makes them the focus of interest in investigating disease pathways, as candidate drug targets, and in evolutionary analyses to identify homologous protein families and possible functional activities. LÄS MER
4. Epigenetic dysregulation in relation to psychiatric traits in adolescence and adulthood
Sammanfattning : Epigenetics has evolved into a key research focus in the field of psychiatry. DNA methylation is the most researched epigenetic mechanism. In paper I-III, 130 and 93 adolescents were randomly recruited at two separate intervals. LÄS MER
5. Brain Structure and Function in Adolescents with Atypical Anorexia Nervosa
Sammanfattning : Atypical anorexia nervosa (AAN) has a high incidence in adolescents, resulting in significant morbidity and mortality. The weight loss is generally less pronounced than that experienced in full-syndrome anorexia nervosa (AN), but the medical consequences can be as severe. LÄS MER
