Sökning: "E-selectin"

Visar resultat 1 - 5 av 26 avhandlingar innehållade ordet E-selectin.

  1. 1. Endothelial-leukocyte interactions

    Detta är en avhandling från Maria Olofsson, Department of Cell and Molecular Biology, Box 94, S-221 00 Lund, Sweden

    Författare :Maria Olofsson; Lund University.; Lunds universitet.; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Histology; endothelial cell; leukocyte; apoptosis; mitochondria; heparin binding protein; vascular permeability; E-selectin; migration; rolling; cytochemistry; histochemistry; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur;

    Sammanfattning : This thesis describes early inflammatory responses involving interactions between leukocytes and the endothelial lining of the blood vessel wall. An adhesion molecule, E-selectin, which is upregulated on interleukin-1 activated endothelium, was found to mediate rolling between leukocytes and endothelial cells in vivo. LÄS MER

  2. 2. On the role of mast cells in chemokine-induced leukocyte recruitment

    Detta är en avhandling från Department of Clinical Sciences, Lund University

    Författare :Yusheng Wang; Lund University.; Lunds universitet.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chemokines; mast cells; TNF-alpha; dexamethasone; P-selectin; E-selectin; activation; Medicine human and vertebrates ; endothelial cells; adhesion; Neutrophil; Medicin människa och djur ; recruitment;

    Sammanfattning : Leukocyte recruitment is considered to playa key role in numerous inflammatory diseases. Tissue accumulation of Jeukocytes is a multi-steps process comprising rolling, adhesion and transmigration. LÄS MER

  3. 3. Systemic sclerosis vascular, pulmonary and immunological aspects

    Detta är en avhandling från Umeå : Reumatologi

    Författare :Grethe Neumann Andersen; Umeå universitet.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic sclerosis; interstitial lung disease; MMP-9; Th1 Th2; transcription factors; NO; iNOS; E-selectin; endothelium-dependent dilation; endothelium-independent dilation.; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Rheumatology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Reumatologi;

    Sammanfattning : In systemic sclerosis (SSc), interstitial lung disease (ILD) and engagement of the vascular system lead to increased morbidity and mortality.The aim of this thesis was to elucidate, in a consecutively included cohort of SSc (limited and diffuse) patients (n = 33), the T cell cytokine profile driving the disease in ILD and to explore the role of matrix metalloproteinase 9 (MMP-9) and its inhibitor: tissue inhibitor of metalloproteinase 1 (TIMP-1) in the extracellular matrix (ECM) degrading process leading to fibrous scarring and honey combing. LÄS MER

  4. 4. Role of glycosylation in regulation of E-selectin expression on endothelial cells

    Detta är en avhandling från Linköping : Linköpings universitet

    Författare :Jan Strindhall; Linköpings universitet.; Linköpings universitet.; [1997]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : Endothelial cells located on the vessel walls play an important role in inflammation. In response to cytokines or other inflammatory mediators endothelial cells will express different cell adhesion molecules that are involved in binding of circulating leukocytes to the endothelium. LÄS MER

  5. 5. Innate immune response in human endothelial cells : characterization and regulation of E-selectin, ICAM-I and cytokine expression and the role of Staphylococcus aureus

    Detta är en avhandling från Linköping : Linköpings universitet

    Författare :Jan Strindhall; Linköpings universitet.; Linköpings universitet.; [2003]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : Endothelial cells located on the vessel walls play an important role in inflammation. In response to cytokines or other inflammatory mediators such as microorganisms, endothelial cells express cell adhesion molecules such as E-selectin and ICAM-1 that are involved in binding circulating leukocytes to the endothelium. LÄS MER