Sökning: "Cancer and oncology"

Visar resultat 36 - 40 av 967 avhandlingar innehållade orden Cancer and oncology.

1. 36. Chemoradiation in Gastrointestinal Cancer

   Författare :Adalsteinn Gunnlaugsson; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biliary tract cancer; capecitabine; cholangiocarcinoma; chemoradiation; colon cancer; enteritis 5-fluorouracil; gallbladder cancer; oxaliplatin; pancreatic cancer; rectal cancer.;

   Sammanfattning : Locally advanced inextirpable gastrointestinal cancer has poor prognosis and is associated with high morbidity. One treatment option is to use radiotherapy, often combined with chemotherapy (chemoradiation), either as preoperative treatment to facilitate surgery or in the palliative setting to relieve symptoms. LÄS MER

3. 37. Copy Number Analysis of Cancer

   Författare :Markus Mayrhofer; Anders Isaksson; Simon Tavaré; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chromosomes; oncology; bioinformatics; Bioinformatik; Bioinformatics; Oncology; Onkologi; Clinical Genetics; Klinisk genetik;

   Sammanfattning : By accurately describing cancer genomes, we may link genomic mutations to phenotypic effects and eventually treat cancer patients based on the molecular cause of their disease, rather than generalizing treatment based on cell morphology or tissue of origin.Alteration of DNA copy number is a driving mutational process in the formation and progression of cancer. LÄS MER

4. 38. Estrogen receptor alpha and beta in breast cancer - gene expression profiles and clinical implications

   Författare :Sofia Gruvberger; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; oncology; cancerology; Cytologi; onkologi; cancer; Cytology; artificial neural networks; gene expression profiling; microarray; tamoxifen; adjuvant endocrine therapy; ER; estrogen receptor beta; Breast cancer; estrogen receptor alpha; Clinical biology;

   Sammanfattning : Breast cancer is the most common malignancy in women in the Western world with about 10% of women developing breast cancer during their lifetime, of which one third will eventually succumb to the metastatic form of the disease. Breast cancer arises from the epithelial cells of the breast mammary gland, but the mechanisms involved in tumor initiation, progression, and metastasis are still not fully understood. LÄS MER

5. 39. Molecular and Cellular Complexity of Glioma : Highlights on the Double-Edged-Sword of Infiltration Versus Proliferation and the Involvement of T Cells

   Författare :Demet Çağlayan; Bengt Westermark; Maria Ferletta; Ana Martin-Villalba; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioma; Sox2; Sox21; Snail; Bone morphogenetic protein; Sleeping Beauty; Gliomatosis Cerebri; T lymphocytes; T regulatory lymphocytes; Oncology; Onkologi; Biology; Biologi;

   Sammanfattning : Glioblastoma multiforme (GBM), the most common and malignant brain tumor, is characterized by high molecular and cellular heterogeneity within and among tumors. Parameters such as invasive growth, infiltration of immune cells and endothelial proliferation contribute in a systemic manner to maintain the malignancy. LÄS MER

7. 40. Quiescent cancer cells : Three-dimensional cell models for evaluation of new therapeutics

   Författare :Frida Ek; Mårten Fryknäs; Malin Jarvius; Rolf Larsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; cancer cell quiescence; dormancy; three-dimensional; multicellular tumor spheroids; model development; cancer pharmacology; mitochondria; OXPHOS; colorectal carcinoma; hepatocellular carcinoma; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Inadequate metabolic conditions in solid tumors lead to the formation of quiescent cancer cells that are suspended in a transient cell cycle arrest. When conditions change, quiescent cancer cells can re-enter the cell cycle and cause recurrence. LÄS MER