Sökning: "Matti Sällberg"

Hittade 3 avhandlingar innehållade orden Matti Sällberg.

  1. 1. Studies on Hepatitis B Vaccination and Factors Associated with the Vaccine Response

    Författare :Kristina Cardell; Aril Frydén; Matti Sällberg; Clas Ahlm; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Hepatitis B virus causes liver disease and up to 2 billion people have been in contact with the virus world wide. It can cause both acute and chronic disease. The routes for transmission are through blood, mother to infant at time of delivery and sexually. LÄS MER

  3. 2. Laboratory methods for investigation of the immunological orchestra in response to pathogens

    Författare :Hanna Carlsson; Ivar Tjernberg; Christina Ekerfelt; Kristina Nilsson Ekdahl; Jorma Hinkula; Matti Sällberg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Borrelia; Influenza; Immunology; Immune response; Cellmediated; Serological; Subclinical; ELISA; Luminex; Proximity extension assay;

    Sammanfattning : Laboratory methods used for investigation of immune response often involve collection of whole blood and analysis of different biomarkers in blood components or generated from pathogen stimulation of whole blood or peripheral blood mononuclear cells (PBMC). Methods used to measure biomarkers are for example enzyme-linked immunosorbent assay (ELISA) which measures one biomarker at a time or multiplex assays for example x-unknown, multi-analyte profiling (xMAP) by Luminex or proximity extension assay (PEA), which can measure up to just over 3000 biomarkers at a time. LÄS MER

  4. 3. Vaccine development strategies applied to the Plasmodium falciparum malaria antigen 332

    Författare :Nina-Maria Vasconcelos; Klavs Berzins; Matti Sällberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; malaria; sub-unit vaccines; immunogenicity; antibody response; antigen Pf332; Immunology; Immunologi;

    Sammanfattning : Malaria is one of the major infectious diseases in the world with regard to mortality and morbidity, and the development of a vaccine against the malaria parasite Plasmodium falciparum is considered of high priority. The aim of the work presented in this thesis was to develop and characterize recombinant vaccine constructs based on the P. LÄS MER