Sökning: "CBF"

Visar resultat 6 - 10 av 59 avhandlingar innehållade ordet CBF.

1. 6. Studies of penta-decameric binding proteins: AP-4 and CBF-A

   Författare :Alaitz Aranburu; Immunologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; transplantation; Metabolism; serologi; metabolism; Biokemi; serology; Immunology; hnRNP H; NPM; CBF-A; AP-4; transcription; B cells; immunoglobulin; Immunologi;

   Sammanfattning : Each immunoglobulin (Ig) V gene segment contains an upstream promoter region. The octamer element and the TATA box are the only elements that are conserved in all Ig promoters. The presence of the octamer element is necessary, but not sufficient to support high levels of transcription. LÄS MER

3. 7. Clinical Bedside Studies of Cerebral Blood Flow in Severe Subarachnoid Hemorrhage Using Xenon CT

   Författare :Henrik Engquist; Per Enblad; Elham Rostami; Anders Lewén; Marianne Juhler; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Subarachnoid hemorrhage; delayed cerebral ischemia; cerebral blood flow; HHH-therapy; triple-H; xenon CT; XeCT; cerebral microdialysis; Neurokirurgi; Neurosurgery;

   Sammanfattning : Aneurysmal subarachnoid hemorrhage (SAH) is frequently complicated by delayed cerebral ischemia (DCI), contributing to poor outcome. Particularly for patients in poor neurological state, prediction of the acute clinical course is difficult, as is the early detection of DCI. LÄS MER

4. 8. Cerebral Blood Flow and Cognition. Clinical studies on Dementia and Cognitive Decline

   Författare :Arkadiusz Siennicki-Lantz; Geriatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gerontology; Gerontologi; vascular risk factors; carotid ultrasound; peripheral arterial disease; orthostatic hypotension; blood pressure; ageing; SPECT; cerebral blood flow; cognition; Dementia; Alzheimer’s disease;

   Sammanfattning : The importance of early detection of brain changes during ageing has been recognised. Single photon emission computed tomography (SPECT) is a method used for estimation of cerebral blood flow (CBF) in clinical work and in research. LÄS MER

5. 9. Optimisation and Validation of Dynamic Susceptibility Contrast MRI Perfusion Measurements

   Författare :Linda Knutsson; Lund Medicinsk strålningsfysik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nukleärmedicin; radiobiologi; Nuclear medicine; radiobiology; radiologi; tomografi; medicinsk instrumentering; tomography; medical instrumentation; Clinical physics; cerebral blood volume; mean transit time; cerebral blood flow; perfusion; dynamic susceptibility contrast MRI arterial input function; Klinisk fysiologi; radiology;

   Sammanfattning : The studies presented in this thesis concern the optimisation and evaluation of the dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) technique for the assessment of perfusion-related parameters of the brain, such as cerebral blood flow (CBF), cerebral blood volume (CBV) and mean transit time (MTT). Several methodological factors influence these measurements, for example, contrast-agent administration, arterial input function (AIF) registration, choice of deconvolution algorithm and the choice of pulse-sequence parameters. LÄS MER

7. 10. Studies of mRNA transport and localization

   Författare :Chandrasekhar Saki Raju; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : During mRNA biogenesis, a subset of newly exported mRNA is assembled into larger RNA granules which are transported to subcellular compartments for localized translation. These mechanisms are critical for asymmetric mRNA and protein distribution and have profound impact on cellular physiology. LÄS MER