Sökning: "Anders Sjöstedt"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden Anders Sjöstedt.

  1. 1. Improved diagnosis and prediction of community-acquired pneumonia

    Författare :Alicia Edin; Anders F. Johansson; Anders Sjöstedt; Annika Allard; Thomas Schön; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Community-acquired pneumonia; infection; diagnosis; qPCR; metabolites; metabolomics;

    Sammanfattning : Community-acquired pneumonia (CAP) is a major cause of morbidity and mortality worldwide. Although there is wide variation in the microbial etiology, CAP may manifest with similar symptoms, making institution of proper treatment challenging. LÄS MER

  3. 2. A microarray analysis of the host response to infection with Francisella tularensis

    Författare :Henrik Andersson; Anders Sjöstedt; David Stenger; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella tularensis; tularemia; host response; gene expression; microarray; Clinical bacteriology; Klinisk bakteriologi;

    Sammanfattning : Francisella tularensis is a gram-negative bacterium that is the cause of the serious and sometimes fatal disease, tularemia, in a wide range of animal species and in humans. The response of cells of the mouse macrophage cell line J774 to infection with Francisella tularensis LVS was analyzed by means of a DNA microarray. LÄS MER

  4. 3. Tularemia : epidemiological, clinical and diagnostic aspects

    Författare :Henrik Eliasson; Erik Bäck; Anders Sjöstedt; Clas Ahlm; Örebro universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Francisella; tularemia; epidemiology; case-control; diagnosis; PCR; clinical characteristics; immunology; ELISA; lymphocyte stimulation; Medicine; Medicin; Infektionssjukdomar; Infectious Diseases;

    Sammanfattning : Tularemia is a zoonosis caused by the small, fastidious, gram-negative rod Francisella tularensis that appears over almost the entire Northern Hemisphere. In Sweden, tularemia has appeared mainly in restricted areas in northern parts of central Sweden. LÄS MER

  5. 4. The oxidative stress response of Francisella tularensis

    Författare :Marie Honn; Anders Sjöstedt; Helena Lindgren; Andres Melendez; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella tularensis; FupA; MglA; OxyR; ROS; oxidative stress; molekylärbiologi; Molecular Biology;

    Sammanfattning : Francisella tularensis is capable of infecting numerous cell types, including professional phagocytes. Upon phagocytosis, F. tularensis resides within the phagosome before escaping into the cytosol to replicate. Phagocytes constitute a hostile environment rich in ROS, which are employed as a means of killing pathogens. LÄS MER

  7. 5. The genetic composition and diversity of Francisella tularensis

    Författare :Pär Larsson; Anders Sjöstedt; Andrew K. Benson; Umeå universitet; []
    Nyckelord :Microbiology; tularemia; genotyping; evolution; microarray; genome sequencing; virulence; genome reduction; Mikrobiologi; Francisella tularensis; klinisk bakteriologi; Clinical Bacteriology;

    Sammanfattning : Francisella tularensis is the causative agent of the debilitating, sometimes fatal zoonotic disease tularemia. To date, little information has been available on the genetic makeup of this pathogen, its evolution, and the genetic differences which characterize subspecific lineages. These are the main areas addressed in this thesis. LÄS MER