Sökning: "OxyR"

Hittade 2 avhandlingar innehållade ordet OxyR.

  1. 1. The oxidative stress response of Francisella tularensis

    Författare :Marie Honn; Anders Sjöstedt; Helena Lindgren; Andres Melendez; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella tularensis; FupA; MglA; OxyR; ROS; oxidative stress; molekylärbiologi; Molecular Biology;

    Sammanfattning : Francisella tularensis is capable of infecting numerous cell types, including professional phagocytes. Upon phagocytosis, F. tularensis resides within the phagosome before escaping into the cytosol to replicate. Phagocytes constitute a hostile environment rich in ROS, which are employed as a means of killing pathogens. LÄS MER

  3. 2. Characterization and function of Escherichia coli glutaredoxins

    Författare :Aristi Potamitou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Escherichia coli employs two separate pathways, driven by NADPH to reduce protein disulfides: the thioredoxin and glutaredoxin systems. Both systems function via redox active disulfides and are involved in many cellular functions including, the synthesis of DNA building blocks (by reducing the essential enzyme ribonucleotide reductase), the generation of reduced sulfur (via PAPS reductase), and the repair of oxidative damage to protein (by methionine sulfoxide reductase). LÄS MER