Sökning: "syntes"

Visar resultat 1 - 5 av 462 avhandlingar innehållade ordet syntes.

  1. 1. Innovation- och säkerhetsvetenskap : En fruktbar syntes

    Författare :Tommy Torsne; Carl Rollenhagen; Björn Wahlström; Mälardalens högskola; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Innovation; Risk; Säkerhet; Förändring; INTERDISCIPLINARY RESEARCH AREAS; TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN; Innovation and Design; innovation och design;

    Sammanfattning : The foundation for the thesis is a literature study within two areas: safety and innovation science. In the thesis safety science will revolve around how different methods and various models are used to identify and reduce risks, i.e. to secure the functionality within limited systems. LÄS MER

  3. 2. Optimering i organisk syntes : betingelser, system, syntesvägar

    Författare :Lars Hansson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Optimization; Response surface method; PLS method; Silylation; Enolether; Unsaturated ketones; Diketones; Geosmin synthesis; Onepot procedure;

    Sammanfattning : This thesis deals with different optimization problems encountered in organic synthesis. The use of response surface, sequential simplex and PLS techniques, for simultanious optimization of yield and suppression of side reactions is investigated. This is illustrated by an example of enamine synthesis, were a side reaction was a serious problem. LÄS MER

  4. 3. An Organic Chemistry Odyssey : Imaging Mass Spectrometry in Neurotherapeutics, Asymmetric Methodology Development and Natural Product Synthesis

    Författare :Marvin Villacrez; Kemisk biologi med inriktning mot läkemedelsutveckling; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Masspektrometri; totalsyntes; avbildande massspektrometri; MALDI avbildande massspektrometri; asymmetrisk syntes; farmakokinetik; dynamisk kinetisk resolution; Aasymetrisk överföringshydrogenering; klozapin; Läkemedelsmetabolism; läkemedelsdistribution; aminoalkoholer; Aspidophylline A; mass spectromery; Imaging mass spectrometry; Total synthesis; Dynamic kinetic resolution; asymmetric transfer hydrogenation; Aspidophylline A; Drug distribution; Drug metabolism; Drug Metabolism and Mass Spectrometry Imaging; MALDI mass spectrometry imaging; clozapine; amino alcohols; pharmacokinetics;

    Sammanfattning : The development of imaging technologies and brain models is crucial for advancements in neurotherapeutic drug discovery and development. They assume a critical role in evaluating essential parameters such as drug blood-brain barrier (BBB) permeation, distribution, and metabolism, all of which are vital for the development of safe and effective medications. LÄS MER

  5. 4. Synthesis of Aldehyde-Functionalized Building Blocks and Their Use for the Cyclization of Peptides : Applications to Angiotensin II

    Författare :Petra Johannesson; Rob M. J. Liskamp; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Synthesis; Aldehyde; Cyclization; Peptide; Angiotensin II; Ang II; Bioactive Conformation; Solid Phase Peptide Synthesis; Dimethyl Acetal; Farmaceutisk kemi; Syntes; Aldehyd; Cyklisering; Peptid; Bioaktiv konformation; Fast-fas peptidsyntes; Dimetylacetal; Pharmaceutical chemistry; Farmaceutisk kemi; Organic Pharmaceutical Chemistry; organisk farmaceutisk kemi;

    Sammanfattning : This study addresses the issue of how to convert peptides into drug-like non- peptides with retained biological activities at peptide receptors. Angiotensin II (Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, Ang II) was used as a model peptide. LÄS MER

  7. 5. Structure and Properties Investigations of the La2Co1+z(Ti1-xMgx)1-zO6 Perovskite System

    Författare :Samrand Shafeie; Gunnar Svensson; Mari-Ann Einarsrud; Mats Johnsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; solid oxide fuel cell; SOFC; LaCoO3; cobaltates; cobalt oxide; perovskite; XANES; XRD; Neutron powder diffraction; thermal expansion; electronic conductivity; magnetism; citrate; electron diffraction; synthesis; phase diagram; spin state; fast fas oxid bränslecell; LaCoO3; koboltoxid; perovskit; XANES; XRD; neutron diffraktion; elektron diffraktion; termisk expansion; elektrisk ledningsförmåga; magnetism; citrat; SOFC; syntes; fasdiagram; spin tillstånd; Solid state chemistry; Fasta tillståndets kemi; Materials chemistry; Materialkemi; Structural Chemistry; strukturkemi; Materials Chemistry; materialkemi;

    Sammanfattning : Perovskite based materials have great potentials for various energy applications and the search for new materials for uses in SOFCs has largely been concentrated to this class of compounds. In this search, we have studied perovskite phases in the system La2Co1+z(Ti1-xMgx)1-zO6, with 0  x 0.9 and z = 0.0, 0. LÄS MER