Sökning: "synthesis"

Visar resultat 1 - 5 av 3340 avhandlingar innehållade ordet synthesis.

  1. 1. Stereoselective Synthesis of Amino Alcohols : Applications to Natural Product Synthesis

    Författare :Staffan Torssell; Peter Somfai; Pher G Andersson; KTH; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Amino alcohol; asymmetric 1.3-dipolar cycloaddition; azomethine ylide; carbenoid; carbonyl ylide; cross-metathesis; omuralide; oxazolidine; rhodium; sphingosine; stemoamide; stereoselective synthesis; total synthesis.; Organic chemistry; Organisk kemi;

    Sammanfattning : This thesis is divided into four separate parts with amino alcohols as the common feature. The first part of the thesis describes the development of an efficient three-component approach to the synthesis of α-hydroxy-β-amino esters. LÄS MER

  2. 2. Approaches to soft drug analogues of dihydrofolate reductase inhibitors : Design and synthesis

    Författare :Malin Graffner Nordberg; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; soft drug; dihydrofolate reductase; synthesis; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi; Organic Pharmaceutical Chemistry; Organisk farmaceutisk kemi;

    Sammanfattning : The main objective of the research described in this thesis has been the design and synthesis of inhibitors of the enzyme dihydrofolate reductase (DHFR) intended for local administration and devoid of systemic side-effects. The blocking of the enzymatic activity of DHFR is a key element in the treatment of many diseases, including cancer, bacterial and protozoal infections, and also opportunistic infections associated with AIDS (Pneumocystis carinii pneumonia, PCP). LÄS MER

  3. 3. Absolute Asymmetric Synthesis

    Författare :Anders Lennartson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :absolute asymmetric synthesis; enantioselective synthesis; chirality; optical resolution; spontaneous resolution; conglomerate; organozinc reagents; organometallic chemistry; coordination chemistry; supramolecular chemistry; intermolecular interactions;

    Sammanfattning : Absolute asymmetric synthesis is the synthesis of optically active products from achiral or racemic precursors only. This has generally been regarded as impossible and is relevant in the discussion of the origins of biomolecular homochirality. LÄS MER

  4. 4. Parabolic Synthesis

    Författare :Erik Hertz; Peter Nilsson; Oscar Gustafsson; Sweden Lund Lund University LTH Department of Electrical and Information Technology Faculty of Engineering; []

    Sammanfattning : Many consumer products, such as within the computer areas, computer graphics, digital signal processing, communication systems, robotics, navigation, astrophysics, fluid physics, etc. are searching for high computational performance as a consequence of increasingly more advanced algorithms in these applications. LÄS MER

  5. 5. Pheromone Synthesis : Conjugated Diene Systems and Oxygenated Carene Derivatives

    Författare :Rikard Unelius; Torbjörn Norin; Lars Skatteböl; KTH Organic Chemistry; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; pheromone diene carene derivative; Organic Chemistry; Organisk kemi;

    Sammanfattning : .... LÄS MER