Sökning: "Diketones"

Hittade 5 avhandlingar innehållade ordet Diketones.

  1. 1. Optimering i organisk syntes : betingelser, system, syntesvägar

    Författare :Lars Hansson; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Optimization; Response surface method; PLS method; Silylation; Enolether; Unsaturated ketones; Diketones; Geosmin synthesis; Onepot procedure;

    Sammanfattning : This thesis deals with different optimization problems encountered in organic synthesis. The use of response surface, sequential simplex and PLS techniques, for simultanious optimization of yield and suppression of side reactions is investigated. This is illustrated by an example of enamine synthesis, were a side reaction was a serious problem. LÄS MER

  3. 2. Enzymatic Reduction of Ketones

    Författare :Magnus Carlquist; Teknisk mikrobiologi; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; inhibition; flavonoids; anthracyclines; human carbonyl reductase 1; kinetic resolution; Asymmetric bioreduction; bicyclic diketones; Saccharomyces cerevisiae; Escherichia coli; AKR; SDR;

    Sammanfattning : Methods have been studied for the production of chiral alcohols, which are of importance in organic synthesis of pharmaceuticals, agro-chemicals and fragrances, etc., through the enzymatic or microbial reduction of ketones. LÄS MER

  4. 3. Synthesis and asymmetric transformations of diols by enzyme- and ruthenium catalysis

    Författare :Karin Leijondahl; Jan-Erling Bäckvall; Kurt Faber; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; dynamic kinetic asymmetric transformation; diols; enzymatic transformations; catalysis; ruthenium; transfer hydrogenation; Organic chemistry; Organisk kemi; Organic Chemistry; organisk kemi;

    Sammanfattning : The major part of this thesis describes the synthesis of aliphatic secondary diols and the development of lipase- and ruthenium-catalyzed asymmetric transformations of these diols. Several acyclic 1,4-diols and 1,5-diols were synthesized, and by combining a lipase-catalyzed asymmetric transformation with a ruthenium-catalyzed epimerization, enantiomerically- and diastereomerically enriched diacetates were obtained. LÄS MER

  5. 4. Engineered Yeast as Biocatalyst for Stereoselective reductions of Dicarbonyl Compounds

    Författare :Ted Johanson; Teknisk mikrobiologi; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; chiral; screening; process optimisation; metabolic engineering; dicarbonyl; biocatalysis; yeast; bioreduction; Biotechnology; Bioteknik;

    Sammanfattning : Chiral building blocks are needed in the chemical and pharmaceutical industries for the production of fine chemicals and pharmaceuticals. The utilisation of microorganisms and enzymes to perform stereoselective reductions of carbonyl compounds is an efficient and widely applied method for the generation of chiral molecules. LÄS MER

  7. 5. Sampling and analysis of polynuclear aromatic hydrocarbons with special reference to automobile exhausts

    Författare :Ulf Stenberg; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : A literature survey concerning the progress in sampling of polynu clear aromatic hydrocarbons, PAH, from automobile exhausts is pre seated. In this conjunction the included analytical methods are discussed, and some emphasis is put on injection technique and column performance. LÄS MER