Sökning: "Pharmaceutical chemistry"
Visar resultat 1 - 5 av 243 avhandlingar innehållade orden Pharmaceutical chemistry.
1. On the Versatility of Microwave-Assisted Chemistry : Exemplified by Applications in Medicinal Chemistry, Heterocyclic Chemistry and Biochemistry
Sammanfattning : Today, the demand for speed in drug discovery is constantly increasing, particularly in the iterative processes of hit validation and expansion and lead optimization. Irradiation with microwaves (MWs) has been applied in the area of organic synthesis to accelerate chemical reactions and to facilitate the generation of new chemical entities since 1986. LÄS MER
2. Pilicides and Curlicides : Design, synthesis, and evaluation of novel antibacterial agents targeting bacterial virulence
Sammanfattning : New strategies are needed to counter the growing problem of bacterial resistance to antibiotics. One such strategy is to design compounds that target bacterial virulence, which could work separately or in concert with conventional bacteriostatic or bactericidal antibiotics. LÄS MER
3. Additive-Driven Improvements in Interfacial Properties and Processing of TMP-Polymer Composites
Sammanfattning : Efforts to address environmental concerns have resulted in new regulations designed to plan the reduction of plastic and synthetic polymer usage, necessitating the search for sustainable natural alternatives with comparable cost-effectiveness and mechanical performance. Thermomechanical pulp (TMP) fibres are one of the most affordable natural fibres that have no chemical refining in production, production have a high yield of 90-98% and TMP fibres have been demonstrated to improve the mechanical characteristics (strength, stiffness and toughness) of wood-polymer composites (WPCs) compared to the pure polymer. LÄS MER
4. Development of Palladium-Promoted 11C/12C-Carbonylations and Radiosynthesis of Amyloid PET Ligands
Sammanfattning : In the first part of this thesis, palladium(0)-catalyzed and -mediated carbonylations are discussed. Paper I describes a new method for the safe, efficient use of a solid carbon monoxide source in the synthesis of primary and secondary benzamides. LÄS MER
5. Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides
Sammanfattning : The development of antimicrobial resistance is a great challenge within the health sector around the world. The demand for new efficient treatments is alarming in order to treat various bacterial infections in the near future. Antimicrobial peptides (AMPs) are a group of novel antibiotics that have gain more and more attraction the past decade. LÄS MER