Sökning: "protein metabolism."

Visar resultat 26 - 30 av 872 avhandlingar innehållade orden protein metabolism..

1. 26. The oxidative metabolism by eosinophils : Effects of allergen exposure and interleukin-5

   Författare :Charlotte Woschnagg; Uppsala universitet; []
   Nyckelord :Medical sciences; Eosinophils; allergy; asthma; rhinitis; oxidative metabolism; IL-5; priming; signal transduction; protein phosphorylation; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

   Sammanfattning : In this thesis the oxidative metabolism by blood eosinophils from birch pollen allergic subjects was studied and compared to that by eosinophils from healthy controls, during and out of the pollen season. The effects and mechanisms of in vitro IL-5 priming on blood eosinophils were investigated and compared to the effects of in vivo priming during pollen exposure. LÄS MER

3. 27. Regulation of the cytoskeleton and the adhesiveness of intestinal epithelial cells by leukotriene D4

   Författare :Ramin Massoumi; Institutionen för translationell medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; patologisk anatomi; Patologi allmän ; pathological anatomy; General pathology; PKC; vinculin; actin filament; focal adhesion; LTD4; integrin; cancerology; Cytologi; onkologi; cancer; Biochemistry; Metabolism; Biokemi; metabolism;

   Sammanfattning : Leukotrienes belong to a family of biologically active conjugated trienes that are formed from arachidonic acid via the 5-lipoxygenase pathway and are important mediators of inflammatory reactions. The CysLT1 receptor that specifically serves as receptor for leukotriene D4 (LTD4) has been identified as a G-protein coupled receptor. LÄS MER

4. 28. Ferrochelatase and Magnesiumchelatase: Metal chelation studied with mutants

   Författare :Ulf Olsson; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; chlorophyll; heme; barley; mutants; Magnesium chelatase; ferrochelatase; Metabolism; Biokemi; metabolism;

   Sammanfattning : Magnesium chelatase and ferrochelatase are two very important enzymes, which are involved in chlorophyll and heme biosynthesis, respectively. They both use protoporphyrin IX as substrate but magnesium chelatase inserts a magnesium ion whereas ferrochelatase inserts a ferrous ion. These two enzymes have been studied in this thesis. LÄS MER

5. 29. Development of sensitive cellular assay systems and their application to the identification of "orphan" seven-transmembrane receptors

   Författare :Knut Kotarsky; Slemhinnans immunologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biokemi; Metabolism; Biochemistry; metabolism; leukotrieneB4; thiazolidinedione; 9-HODE; fatty acid; luciferase; GFP; reporter gene; preclinical assay; receptor; GPCR;

   Sammanfattning : Seven-transmembrane, G-protein coupled receptors play a central role in physiology since they facilitate cell communication in multicellular organisms by recognition of a broad range of ligands. They also represent important drug targets. LÄS MER

7. 30. Biosynthesis of decorin and glypican glycosaminoglycan chains

   Författare :Mats Jönsson; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Metabolism; Biochemistry; phosphorylation; biosynthesis; glycosaminoglycan; decorin; glypican; Biokemi; metabolism;

   Sammanfattning : Proteoglycans consist of core proteins substituted with glycosaminoglycan chains. The galactosaminoglycans (GlcUA/IdoUA-GalNAc) and the glucosaminoglycans (GlcUA/IdoUA-GlcNAc) are both initiated on the same tetrasaccharide linkage region GlcUA-Gal-Gal-Xyl-protein. LÄS MER