Sökning: "non-coding RNA"

Visar resultat 21 - 25 av 105 avhandlingar innehållade orden non-coding RNA.

1. 21. Characterization of non-coding mRNA in Epstein-Barr virus

   Författare :Åsa Isaksson; Göteborgs universitet; []
   Nyckelord :Epstein-Barr virus; EBNA1; IRES; PTLD; alternative splice; nucleotide substitution; protein interactions;

   Sammanfattning : Epstein-Barr virus (EBV) is a human gammaherpesvirus that infects lymphoid and epithelial cells. The virus is the causative agent of infectious mononucleosis, a self-limiting lymphoproliferative disease, and it is additionally associated with various malignancies including Burkitt?s lymphoma, Hodgkin?s disease and lymphoproliferative syndromes in immunocompromised individuals. LÄS MER

3. 22. Functional analysis of long non-coding RNAs in cancer

   Författare :Linda Vidarsdottir; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : For years the functional role of noncoding RNAs was greatly underestimated. Whole genome RNA sequencing projects that unraveled pervasive transcription emitting from large parts of the human genome changed those perspectives and prompted scientists to further look into the involvement of noncoding RNAs (ncRNAs) in development and disease. LÄS MER

4. 23. Small RNAs, Big Consequences : Post-transcriptional Regulation and Adaptive Immunity in Bacteria

   Författare :Mirthe Hoekzema; Gerhart E. H. Wagner; Magnus Lundgren; Kai Papenfort; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; small RNA; sRNA; non-coding RNA; Hfq; gene regulation; post-transcriptional regulation; biofilm; OmrA; OmrB; toxin-antitoxin; TisB; IstR-1; Persisters; CRISPR-Cas; CRISPR-Cas adaptation reporter; Escherichia coli; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

   Sammanfattning : It is nowadays widely accepted that non-coding RNAs play important roles in post-transcriptional regulation of genes in all kingdoms of life. In bacteria, the largest group of RNA regulators are the small RNAs (sRNAs). LÄS MER

5. 24. Chromosome-specific adaptations of RNA stability and the roles of the roX RNAs in dosage compensation

   Författare :Marie-Line Faucillion; Jan Larsson; Jean-Yves Roignant; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila melanogaster; dosage compensation; buffering; RNA stability; RNA decay; RNA half-life; RNA-seq; genome-wide; sex chromosomes; evolution; roX1; roX2; POF; MSL; molekylärbiologi; Molecular Biology;

   Sammanfattning : Sex chromosomes evolved from an ancient pair of autosomes and the Y chromosome lost most of its genetic information in the process. This created two kinds of genomic imbalances: the first one between males (XY) and females (XX) and the second one between the sex chromosomes and the autosomes (X:AA). LÄS MER

7. 25. Macromolecular Matchmaking : Mechanisms and Biology of Bacterial Small RNAs

   Författare :Erik Holmqvist; E. Gerhart H. Wagner; Udo Bläsi; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Small RNA; sRNA; non-coding RNA; antisense; gene regulation; post-transcriptional regulation; translational control; outer membrane protein; OmpA; MicA; biofilm; flagella; curli; bistability; Lrp; MicF; CsgD; FlgM; OmrA; OmrB; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

   Sammanfattning : Cells sense the properties of the surrounding environment and convert this information into changes in gene expression. Bacteria are, in contrast to many multi-cellular eukaryotes, remarkable in their ability to cope with rapid environmental changes and to endure harsh and extreme milieus. LÄS MER