Sökning: "Hfq"

Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet Hfq.

  1. 1. Identification of new virulence factors in Francisella tularensis

    Författare :Anna-Lena Forslund; Åke Forsberg; Elisabeth Carniel; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Francisella tularensis; regulation; virulence; Hfq; DsbA; type IV pili; membrane; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : Francisella tularensis, the causative agent of tularemia, is a highly virulent bacterium with an infection dose of less than ten bacteria. The ability of a pathogen to cause infection relies on different virulence mechanisms, but in Francisella tularensis relatively few virulence factors are known. Two F. LÄS MER

  3. 2. CopA and CopT: The Perfect RNA Couple

    Författare :Jacoba G. Slagter-Jäger; Gerhart Wagner; Wolfgang Nellen; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microbiology; antisense RNA; plasmid; U-turn; four-way junction; RNA-RNA interaction; Hfq; Mikrobiologi; Microbiology; Mikrobiologi; mikrobiologi; Microbiology;

    Sammanfattning : Antisense RNAs regulate gene expression in many bacterial systems. The best characterized examples are from prokaryotic accessory elements such as phages, plasmids and transposons. Many of these antisense RNAs have been identified as plasmid copy number regulators where they regulate the replication frequency of the plasmid by negative feedback. LÄS MER

  4. 3. Small RNAs, Big Consequences : Post-transcriptional Regulation and Adaptive Immunity in Bacteria

    Författare :Mirthe Hoekzema; Gerhart E. H. Wagner; Magnus Lundgren; Kai Papenfort; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; small RNA; sRNA; non-coding RNA; Hfq; gene regulation; post-transcriptional regulation; biofilm; OmrA; OmrB; toxin-antitoxin; TisB; IstR-1; Persisters; CRISPR-Cas; CRISPR-Cas adaptation reporter; Escherichia coli; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Sammanfattning : It is nowadays widely accepted that non-coding RNAs play important roles in post-transcriptional regulation of genes in all kingdoms of life. In bacteria, the largest group of RNA regulators are the small RNAs (sRNAs). LÄS MER

  5. 4. Multiple regulatory inputs for hierarchical control of phenol catabolism by Pseudomonas putida

    Författare :W. K. Anjana Madhushani; Victoria Shingler; Livia Leoni; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; P. putida; Phenol catabolism; dmpR; dmp-System; 5’-LR; Carbon Catabolite Repression; Transcriptional Translational regulation; Crc; CrcZ; CrcY; Hfq;

    Sammanfattning : Metabolically versatile bacteria have evolved diverse strategies to adapt to different environmental niches and respond to fluctuating physico-chemical parameters. In order to survive in soil and water habitats, they employ specific and global regulatory circuits to integrate external and internal signals to counteract stress and optimise their energy status. LÄS MER

  7. 5. Hfq- and sRNA-mediated regulation in Neisseria meningitidis

    Författare :Jens Karlsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neisseria meningitidis, also known as the meningococcus, is a human-specific pathogen that commonly colonises the nasopharynx without causing disease. For reasons unknown, N. meningitidis can traverse the nasopharyngeal epithelium and enter the bloodstream, causing invasive meningococcal disease manifesting in septicaemia and/or meningitis. LÄS MER